Odah Mosad M, Ewis Ashraf A, Alessi Awad A, Alhasani Turki M, Alghanmi Ali A, Almarhabi Abdulrahman A, Almuashi Ibrahim M, Almathami Ali A, Alfakieh Hassan O, Alkudaysi Fuad M, Alnashri Ibrahim A, Alnashri Hassan I, Awad Mohammed A, Alammari Mohammed S, Alessa Adnan A
Biochemistry, Umm Al-Qura University, Al-Qunfudah, SAU.
Public Health, Umm Al-Qura University, Al-Qunfudah, SAU.
Cureus. 2021 Dec 10;13(12):e20325. doi: 10.7759/cureus.20325. eCollection 2021 Dec.
Background and objective Gastroesophageal reflux disease (GERD) is one of the most common gastrointestinal diseases worldwide. It causes an unpleasant effect on patients' lives and may lead to serious complications resulting in a significant burden on healthcare systems. Despite being a common gastrointestinal disease, very few studies have been conducted on the condition in Saudi Arabia; and there has never been a study to estimate the prevalence of GERD in the Al-Qunfudah Governorate. In light of this, we conducted this study with an aim to assess the prevalence of GERD and its associated risk factors among the Al-Qunfudah population. Methods A cross-sectional study was conducted in the Al-Qunfudah Governorate by using an online self-administrated questionnaire that was shared through social media during the first week of January 2021. The questionnaire consisted of a general section on sociodemographic data and a section on the diagnosis of GERD based on the validated gastroesophageal reflux disease questionnaire (GERD-Q). A total of 1,180 eligible participants responded to the questionnaire. Results Nearly one-third (32.9%) of the study participants had GERD based on their reported symptoms and calculated scores (GERD-Q score ≥8). About 14.8% of the participants (175/1,180) reported that they had already been diagnosed with GERD before their participation in our survey. Regarding risk factors of GERD, about 35% reported experiencing psychological stress, 28.3% had a family member diagnosed with GERD, and 18.1% were smokers; 49.4% of the participants had their symptoms aggravated by consuming fatty or fried food and 46.7% by spicy food. One of the factors that helped to relieve GERD symptoms was avoiding symptom-aggravating food, as reported by more than half (50.7%) of the participants. Conclusion The prevalence of GERD in the Al-Qunfudah population is high as the condition has affected one-third of the adult population. Our study confirms that male gender, age of 30 years or above, being overweight or obese, being married, smoking habit, use of non-steroidal anti-inflammatory drugs (NSAIDs), having psychological stress, being asthmatic, or having a family history of GERD are factors that significantly increase the likelihood of developing GERD. The reported risk factors include experiencing psychological stress, a family history of GERD, high BMI, and smoking.
背景与目的 胃食管反流病(GERD)是全球最常见的胃肠道疾病之一。它对患者的生活产生不良影响,并可能导致严重并发症,给医疗系统带来沉重负担。尽管GERD是一种常见的胃肠道疾病,但沙特阿拉伯针对该疾病的研究却很少;而且从未有过关于估计库夫达省GERD患病率的研究。有鉴于此,我们开展了这项研究,旨在评估库夫达人群中GERD的患病率及其相关危险因素。
方法 2021年1月的第一周,我们在库夫达省开展了一项横断面研究,使用通过社交媒体分享的在线自填问卷。问卷包括一个关于社会人口统计学数据的一般部分和一个基于经过验证的胃食管反流病问卷(GERD-Q)的GERD诊断部分。共有1180名符合条件的参与者回复了问卷。
结果 根据报告的症状和计算得分(GERD-Q得分≥8),近三分之一(32.9%)的研究参与者患有GERD。约14.8%的参与者(175/1180)报告称,在参与我们的调查之前,他们已经被诊断出患有GERD。关于GERD的危险因素,约35%的人报告经历过心理压力,28.3%的人有家庭成员被诊断出患有GERD,18.1%的人吸烟;49.4%的参与者食用高脂肪或油炸食品会使症状加重,46.7%的参与者食用辛辣食品会使症状加重。超过一半(50.7%)的参与者报告称,有助于缓解GERD症状的因素之一是避免食用会加重症状的食物。
结论 库夫达人群中GERD的患病率很高,因为该疾病影响了三分之一的成年人口。我们的研究证实,男性、30岁及以上、超重或肥胖、已婚、吸烟习惯、使用非甾体抗炎药(NSAIDs)、有心理压力、患有哮喘或有GERD家族史是显著增加患GERD可能性的因素。报告的危险因素包括经历心理压力、有GERD家族史、高体重指数和吸烟。