Nuclear Medicine Department, University Hospital of Bordeaux, Bordeaux, F-33000, France.
University of Bordeaux, CNRS, EPHE, INCIA, UMR 5287, Talence, F-33400, France.
Phys Med Biol. 2022 Feb 1;67(3). doi: 10.1088/1361-6560/ac43fc.
Positron emission tomography (PET) respiratory motion correction has been a subject of great interest for the last twenty years, prompted mainly by the development of multimodality imaging devices such as PET/computed tomography (CT) and PET/magnetic resonance imaging (MRI). PET respiratory motion correction involves a number of steps including acquisition synchronization, motion estimation and finally motion correction. The synchronization steps include the use of different external device systems or data driven approaches which have been gaining ground over the last few years. Patient specific or generic motion models using the respiratory synchronized datasets can be subsequently derived and used for correction either in the image space or within the image reconstruction process. Similar overall approaches can be considered and have been proposed for both PET/CT and PET/MRI devices. Certain variations in the case of PET/MRI include the use of MRI specific sequences for the registration of respiratory motion information. The proposed review includes a comprehensive coverage of all these areas of development in field of PET respiratory motion for different multimodality imaging devices and approaches in terms of synchronization, estimation and subsequent motion correction. Finally, a section on perspectives including the potential clinical usage of these approaches is included.
正电子发射断层扫描（PET）呼吸运动校正已经引起了人们极大的兴趣，主要是由于多模态成像设备的发展，如正电子发射断层扫描/计算机断层扫描（PET/CT）和正电子发射断层扫描/磁共振成像（PET/MRI）。PET 呼吸运动校正涉及多个步骤，包括采集同步、运动估计和最终的运动校正。同步步骤包括使用不同的外部设备系统或数据驱动方法，这些方法在过去几年中得到了广泛应用。随后，可以使用基于呼吸同步数据集的患者特定或通用运动模型来进行校正，无论是在图像空间中还是在图像重建过程中。对于 PET/CT 和 PET/MRI 设备，可以考虑并提出类似的整体方法。在 PET/MRI 的情况下，某些变化包括使用 MRI 特定序列来注册呼吸运动信息。本综述包括对不同多模态成像设备和方法的 PET 呼吸运动领域的所有这些发展领域的全面涵盖，包括同步、估计和随后的运动校正。最后，还包括一个关于这些方法的潜在临床应用的视角部分。
