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非洲因角膜溃疡导致的儿童失明:病因、预防与治疗

Childhood blindness from corneal ulceration in Africa: causes, prevention, and treatment.

作者信息

Foster A, Sommer A

出版信息

Bull World Health Organ. 1986;64(5):619-23.

PMID:3492298
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2490963/
Abstract

Corneal scarring is responsible for approximately 70% of blindness in children in African countries. Recent studies confirm that measles infection is a common predisposing factor and that vitamin A deficiency is responsible for the majority of bilateral corneal ulceration. Herpes simplex keratitis (caused by human (alpha) herpesvirus types 1 and 2), ophthalmia neonatorum, and the use of traditional eye medicines also constitute significant causes of corneal ulceration in children in Africa. Intervention strategies, the management of corneal ulceration in children, and areas for future investigation are discussed.

摘要

在非洲国家,角膜瘢痕导致了约70%的儿童失明。最近的研究证实,麻疹感染是一个常见的诱发因素,而维生素A缺乏是导致大多数双侧角膜溃疡的原因。单纯疱疹性角膜炎(由1型和2型人α疱疹病毒引起)、新生儿眼炎以及使用传统眼药也是非洲儿童角膜溃疡的重要原因。本文讨论了干预策略、儿童角膜溃疡的管理以及未来的研究方向。

相似文献

1
Childhood blindness from corneal ulceration in Africa: causes, prevention, and treatment.非洲因角膜溃疡导致的儿童失明:病因、预防与治疗
Bull World Health Organ. 1986;64(5):619-23.
2
Corneal ulceration, measles, and childhood blindness in Tanzania.坦桑尼亚的角膜溃疡、麻疹与儿童失明
Br J Ophthalmol. 1987 May;71(5):331-43. doi: 10.1136/bjo.71.5.331.
3
Measles, corneal ulceration and childhood blindness: prevention and treatment.麻疹、角膜溃疡与儿童失明:预防与治疗
Trop Doct. 1988 Apr;18(2):74-8. doi: 10.1177/004947558801800213.
4
[Corneal blindness in tropical areas].[热带地区的角膜盲]
Med Trop (Mars). 1995;55(4 Pt 2):445-9.
5
Corneal blindnesses in tropical environment.热带环境中的角膜盲症
Rev Int Trach Pathol Ocul Trop Subtrop Sante Publique. 1990;67:23-138.
6
Corneal blindness: a global perspective.角膜盲:全球视角。
Bull World Health Organ. 2001;79(3):214-21. Epub 2003 Jul 7.
7
[The causes of blindness by corneal diseases in 3,499 cases].[3499例角膜疾病致盲原因分析]
Zhonghua Yan Ke Za Zhi. 1990 May;26(3):151-3.
8
Corneal ulceration following measles in Nigerian children.尼日利亚儿童麻疹后的角膜溃疡
Br J Ophthalmol. 1979 Nov;63(11):720-4. doi: 10.1136/bjo.63.11.720.
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A simple surveillance system for xerophthalmia and childhood corneal ulceration.一种用于干眼症和儿童角膜溃疡的简易监测系统。
Bull World Health Organ. 1986;64(5):725-8.
10
Measles blindness.麻疹致盲
Surv Ophthalmol. 2004 Mar-Apr;49(2):243-55. doi: 10.1016/j.survophthal.2003.12.005.

引用本文的文献

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Inpatient morbidity and mortality of measles in the United States.美国麻疹的住院患者发病率和死亡率。
PLoS One. 2020 Apr 28;15(4):e0231329. doi: 10.1371/journal.pone.0231329. eCollection 2020.
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Measles: An Overview of a Re-Emerging Disease in Children and Immunocompromised Patients.麻疹:儿童及免疫功能低下患者中一种再度出现的疾病概述
Microorganisms. 2020 Feb 18;8(2):276. doi: 10.3390/microorganisms8020276.
3
Etiology of corneal opacification in central Tanzania.坦桑尼亚中部角膜混浊的病因
Int Ophthalmol. 1993 Feb;17(1):47-51. doi: 10.1007/BF00918868.
4
Childhood blindness due to vitamin A deficiency in India: regional variations.印度因维生素A缺乏导致的儿童失明:地区差异
Arch Dis Child. 1995 Apr;72(4):330-3. doi: 10.1136/adc.72.4.330.
5
Vitamin A and measles in Third World children.第三世界国家儿童中的维生素A与麻疹
BMJ. 1990 Dec 1;301(6763):1230-1. doi: 10.1136/bmj.301.6763.1230.
6
The World Health Organization's programme for the prevention of blindness.世界卫生组织预防失明规划
Int Ophthalmol. 1990 May;14(3):211-9. doi: 10.1007/BF00158321.
7
Causes of blindness and visual handicap in the Central African Republic.中非共和国失明和视力障碍的原因。
Br J Ophthalmol. 1991 Jun;75(6):326-8. doi: 10.1136/bjo.75.6.326.
8
Prevalence and causes of vision loss in central Tanzania.坦桑尼亚中部视力丧失的患病率及原因
Int Ophthalmol. 1991 Mar;15(2):123-9. doi: 10.1007/BF00224465.
9
Points of action in the campaign against blindness in developing countries.发展中国家防治失明运动的行动要点。
Doc Ophthalmol. 1991;78(3-4):285-305. doi: 10.1007/BF00165693.

本文引用的文献

1
Xerophthalmia in the presence of kwashiorkor in Nigeria.尼日利亚存在夸休可尔症并发干眼病的情况。
Trop Geogr Med. 1966 Mar;18(1):15-9.
2
Blindness in the Luapula valley.卢阿普拉山谷的失明问题。
Cent Afr J Med. 1967 Sep;13(9):197-201.
3
Xerophthalmia in northern Nigeria.尼日利亚北部的干眼病
Trop Geogr Med. 1971 Sep;23(3):246-9.
4
Measles and xerophthalmia in East Africa.东非的麻疹与干眼病
Trop Geogr Med. 1974 Mar;26(1):39-44.
5
A simple surveillance system for xerophthalmia and childhood corneal ulceration.一种用于干眼症和儿童角膜溃疡的简易监测系统。
Bull World Health Organ. 1986;64(5):725-8.
6
Blindness and visual impairment in southern Malawi.马拉维南部的失明和视力障碍情况。
Bull World Health Organ. 1986;64(4):567-72.
7
Causes of blindness among students in blind school institutions in a developing country.发展中国家盲人学校机构中失明学生的致盲原因。
Br J Ophthalmol. 1976 Sep;60(9):665-8. doi: 10.1136/bjo.60.9.665.
8
Corneal ulceration following measles in Nigerian children.尼日利亚儿童麻疹后的角膜溃疡
Br J Ophthalmol. 1979 Nov;63(11):720-4. doi: 10.1136/bjo.63.11.720.