非洲因角膜溃疡导致的儿童失明：病因、预防与治疗
Childhood blindness from corneal ulceration in Africa: causes, prevention, and treatment.
作者信息
Foster A, Sommer A
出版信息
Bull World Health Organ. 1986;64(5):619-23.
Abstract
Corneal scarring is responsible for approximately 70% of blindness in children in African countries. Recent studies confirm that measles infection is a common predisposing factor and that vitamin A deficiency is responsible for the majority of bilateral corneal ulceration. Herpes simplex keratitis (caused by human (alpha) herpesvirus types 1 and 2), ophthalmia neonatorum, and the use of traditional eye medicines also constitute significant causes of corneal ulceration in children in Africa. Intervention strategies, the management of corneal ulceration in children, and areas for future investigation are discussed.
摘要
在非洲国家，角膜瘢痕导致了约70%的儿童失明。最近的研究证实，麻疹感染是一个常见的诱发因素，而维生素A缺乏是导致大多数双侧角膜溃疡的原因。单纯疱疹性角膜炎（由1型和2型人α疱疹病毒引起）、新生儿眼炎以及使用传统眼药也是非洲儿童角膜溃疡的重要原因。本文讨论了干预策略、儿童角膜溃疡的管理以及未来的研究方向。
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