Department of Pharmacy, Life Science Faculty, Bangabandhu Sheikh Mujibur Rahman Science and Technology University, Gopalganj (Dhaka) 8100, Bangladesh.
Facultad de Ciencias de la Salud, Universidad Arturo Prat, Avda. Arturo Prat 2120, Iquique 1110939, Chile.
Oxid Med Cell Longev. 2021 Dec 10;2021:6349041. doi: 10.1155/2021/6349041. eCollection 2021.
(Thunb.) Cogn. (Cucurbitaceae) is an annual climbing plant, native to Asia with multiple therapeutic uses in traditional medicine. This updated review is aimed at discussing the ethnopharmacological, phytochemical, pharmacological properties, and molecular mechanisms highlighted in preclinical experimental studies and toxicological safety to evaluate the therapeutic potential of this genus. The literature from PubMed, Google Scholar, Elsevier, Springer, Science Direct, and database was analyzed using the basic keyword "." Other searching strategies, including online resources, books, and journals, were used. The taxonomy of the plant has been made by consulting "The Plant List". The results showed that has been used in traditional medicine to treat neurological diseases, kidney disease, fever, and cough accompanied by thick mucus and to fight intestinal worms. The main bioactive compounds contained in have cytotoxic, anti-inflammatory, and anticancer properties. Further safety and efficacy investigations are needed to confirm these beneficial therapeutic effects and also future human clinical studies.
绞股蓝（Thunb.）Cogn.（葫芦科）是一种一年生攀援植物，原产于亚洲，在传统医学中有多种治疗用途。本综述旨在讨论在临床前实验研究中突出显示的民族药理学、植物化学、药理学特性和分子机制，以及毒理学安全性，以评估该属的治疗潜力。使用基本关键字“.”分析了来自 PubMed、Google Scholar、Elsevier、Springer、Science Direct 和数据库的文献。还使用了其他搜索策略，包括在线资源、书籍和期刊。通过咨询“植物名录”对植物的分类进行了分类。结果表明，绞股蓝在传统医学中用于治疗神经系统疾病、肾脏疾病、发热、咳嗽伴浓痰以及驱肠虫。绞股蓝中含有的主要生物活性化合物具有细胞毒性、抗炎和抗癌特性。需要进一步的安全性和疗效研究来证实这些有益的治疗效果，以及未来的人类临床研究。
