Xie Rui, Qiu Bingjie, Chhablani Jay, Zhang Xinyuan
Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Tongren Hospital, Capital Medical University, Beijing, China.
Beijing Retinal and Choroidal Vascular Diseases Study Group, Beijing, China.
Front Med (Lausanne). 2021 Dec 3;8:783519. doi: 10.3389/fmed.2021.783519. eCollection 2021.
The choroid is the main source of blood and nourishment supply to the eye. The dysfunction of the choroid has been implicated in various retinal and choroidal diseases. The identification and in-depth understanding of pachychoroid spectrum disorders are based on the tremendous progress of optical coherence tomography (OCT) technology in recent years, although visibility of choroid is challenging in the era of the time or spectral domain OCT. The recent rapid revolution of OCTs, such as the enhanced depth imaging OCT and the swept-source OCT, has greatly contributed to the significant improvement in the analysis of the morphology and physiology of the choroid precisely, especially to the choroid-scleral boundary and vasculature. The present review highlights the recently available evidence on the measurement methodology and the clinical significance of choroidal thickness in retinal or choroidal disorders.
脉络膜是眼球血液和营养供应的主要来源。脉络膜功能障碍与多种视网膜和脉络膜疾病有关。尽管在时域或频域光学相干断层扫描（OCT）时代，脉络膜的可视化具有挑战性，但近年来光学相干断层扫描（OCT）技术的巨大进步为厚脉络膜谱系疾病的识别和深入理解奠定了基础。OCT的最新快速发展，如增强深度成像OCT和扫频源OCT，极大地促进了对脉络膜形态和生理学分析的显著改善，特别是对脉络膜-巩膜边界和脉管系统的分析。本综述重点介绍了目前关于视网膜或脉络膜疾病中脉络膜厚度测量方法和临床意义的现有证据。
