Nilssen D E, Talseth T, Brodwall E K
Acta Med Scand. 1986;220(5):489-91. doi: 10.1111/j.0954-6820.1986.tb02800.x.
Four cases of antiglomerular basement membrane (antiGBM) antibody mediated disease with unusual features are presented. Lung involvement was absent in one patient whereas the other 3 had Goodpasture's syndrome. Recognition of the nature of the disease was delayed in all cases, due to occurrence during pregnancy in one case and due to the indolent course of the renal injury in the other 3 cases. The therapeutic approach to these variant forms of antiGBM antibody mediated disease is discussed.
本文报告了4例具有不寻常特征的抗肾小球基底膜(antiGBM)抗体介导疾病。其中1例患者无肺部受累,而其他3例患有肺出血肾炎综合征。由于1例发生在妊娠期,另3例肾损伤病程隐匿,所有病例对疾病性质的认识均延迟。本文还讨论了这些抗GBM抗体介导疾病变异形式的治疗方法。