Giggs J A
Soc Sci Med. 1986;23(10):945-61. doi: 10.1016/0277-9536(86)90252-2.
This paper presents the findings of a specifically geographical investigation of the incidence, distribution and social/environmental correlates of mental disorder in Nottingham. Three diagnostic groups were examined, namely schizophrenia and paranoia, the effective psychoses (or manic depression) and the non-psychotic mental disorders. Analysis of two distinct cohorts of first contact patients for both the schizophrenia and affective psychoses diagnoses yielded markedly dissimilar incidence rates. It is therefore suggested that observed variations in the incidence of specific mental disorders between cities probably reflect such nosocomial (i.e. service related) factors as diagnostic accuracy and the levels of local psychiatric services. It is therefore dangerous to ascribe the variations solely to the contrasting social/environmental milieux found in these cities. The spatial distributions of the selected mental disorders within Nottingham were analysed in the context of a set of 12 distinct ecological areas. These areas were derived from a matrix comprising 105 sub-areas and 40 variables via principal components analysis and a non-hierarchical clustering algorithm. Marked spatial variation in the incidence of all the mental disorders was demonstrated via both traditional mapping and probability mapping techniques. Pearson product-moment analysis revealed that the distributions of the two diagnostically distinct schizophrenia and affective psychoses cohorts were virtually identical. The relationships between the inception rates for the mental disorders and social/environmental attributes were analysed. Stepwise multiple regression models for both the principal components and the individual census variables revealed strong and systematic relationships with all the mental disorders. Although such ecological analysis has limited explanatory power it nevertheless provides useful insights into mental disorder-environmental relationships. It is argued that these can be subsequently best examined at a disaggregated (i.e. behavioural) level.
本文介绍了一项针对诺丁汉精神障碍发病率、分布情况以及社会/环境相关因素的专项地理调查结果。研究了三个诊断类别,即精神分裂症与偏执狂、躁郁症(或躁狂抑郁症)以及非精神病性精神障碍。对两个不同队列的首次接触患者进行精神分裂症和情感性精神病诊断分析,得出了明显不同的发病率。因此,有人认为城市间特定精神障碍发病率的观察差异可能反映了诸如诊断准确性和当地精神科服务水平等医院因素(即与服务相关的因素)。因此,将这些差异仅仅归因于这些城市中截然不同的社会/环境背景是危险的。在一组12个不同的生态区域背景下,分析了诺丁汉市内所选精神障碍的空间分布。这些区域是通过主成分分析和非层次聚类算法从一个包含105个子区域和40个变量的矩阵中得出的。通过传统制图和概率制图技术都证明了所有精神障碍发病率存在明显的空间差异。皮尔逊积差分析表明,两个诊断不同的精神分裂症和情感性精神病队列的分布几乎相同。分析了精神障碍发病率与社会/环境属性之间的关系。针对主成分和各个普查变量的逐步多元回归模型显示,与所有精神障碍都存在强烈且系统的关系。尽管这种生态分析的解释力有限,但它仍然为精神障碍与环境的关系提供了有用的见解。有人认为,随后可以在更细分的(即行为)层面上对这些关系进行最佳研究。