Elsharkawy Mohamed, Elrazzaz Mostafa, Ghazal Mohammed, Alhalabi Marah, Soliman Ahmed, Mahmoud Ali, El-Daydamony Eman, Atwan Ahmed, Thanos Aristomenis, Sandhu Harpal Singh, Giridharan Guruprasad, El-Baz Ayman
Bioengineering Department, University of Louisville, Louisville, KY 40292, USA.
Electrical and Computer Engineering Department, College of Engineering, Abu Dhabi University, Abu Dhabi 59911, United Arab Emirates.
Diagnostics (Basel). 2021 Dec 9;11(12):2313. doi: 10.3390/diagnostics11122313.
In developed countries, age-related macular degeneration (AMD), a retinal disease, is the main cause of vision loss in the elderly. Optical Coherence Tomography (OCT) is currently the gold standard for assessing individuals for initial AMD diagnosis. In this paper, we look at how OCT imaging can be used to diagnose AMD. Our main aim is to examine and compare automated computer-aided diagnostic (CAD) systems for diagnosing and grading of AMD. We provide a brief summary, outlining the main aspects of performance assessment and providing a basis for current research in AMD diagnosis. As a result, the only viable alternative is to prevent AMD and stop both this devastating eye condition and unwanted visual impairment. On the other hand, the grading of AMD is very important in order to detect early AMD and prevent patients from reaching advanced AMD disease. In light of this, we explore the remaining issues with automated systems for AMD detection based on OCT imaging, as well as potential directions for diagnosis and monitoring systems based on OCT imaging and telemedicine applications.
在发达国家，年龄相关性黄斑变性（AMD）是一种视网膜疾病，是老年人视力丧失的主要原因。光学相干断层扫描（OCT）是目前用于初步诊断AMD个体评估的金标准。在本文中，我们探讨了OCT成像如何用于诊断AMD。我们的主要目的是检查和比较用于AMD诊断和分级的自动化计算机辅助诊断（CAD）系统。我们提供了一个简要概述，概述了性能评估的主要方面，并为当前AMD诊断研究提供了基础。因此，唯一可行的选择是预防AMD，并阻止这种破坏性的眼部疾病和不必要的视力损害。另一方面，AMD的分级对于检测早期AMD以及防止患者发展到晚期AMD疾病非常重要。有鉴于此，我们探讨了基于OCT成像的AMD检测自动化系统的剩余问题，以及基于OCT成像和远程医疗应用的诊断和监测系统的潜在方向。
