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近期用于提高可及性和远程监测的光学相干断层扫描(OCT)创新技术。

Recent Optical Coherence Tomography (OCT) Innovations for Increased Accessibility and Remote Surveillance.

作者信息

Devine Brigid C, Dogan Alan B, Sobol Warren M

机构信息

College of Medicine, Northeast Ohio Medical University, Rootstown, OH 44272, USA.

Virginia Tech Carilion School of Medicine, Roanoke, VA 24016, USA.

出版信息

Bioengineering (Basel). 2025 Apr 23;12(5):441. doi: 10.3390/bioengineering12050441.


DOI:10.3390/bioengineering12050441
PMID:40428060
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12108957/
Abstract

Optical Coherence Tomography (OCT) has revolutionized the diagnosis and management of retinal diseases, offering high-resolution, cross-sectional imaging that aids in early detection and continuous monitoring. However, traditional OCT devices are limited to clinical settings and require a technician to operate, which poses accessibility challenges such as a lack of appointment availability, patient and family burden of frequent transportation, and heightened healthcare costs, especially when treatable pathology is undetected. With the increasing global burden of retinal conditions such as age-related macular degeneration (AMD) and diabetic retinopathy, there is a critical need for improved accessibility in the detection of retinal diseases. Advances in biomedical engineering have led to innovations such as portable models, community-based systems, and artificial intelligence-enabled image analysis. The SightSync OCT is a community-based, technician-free device designed to enhance accessibility while ensuring secure data transfer and high-quality imaging (6 × 6 mm resolution, 80,000 A-scans/s). With its compact design and potential for remote interpretation, SightSync widens the possibility for community-based screening for vision-threatening retinal diseases. By integrating innovations in OCT imaging, the future of monitoring for retinal disease can be transformed to reduce barriers to care and improve patient outcomes. This article discusses the evolution of OCT technology, its role in the diagnosis and management of retinal diseases, and how novel engineering solutions like SightSync OCT are transforming accessibility in retinal imaging.

摘要

光学相干断层扫描(OCT)彻底改变了视网膜疾病的诊断和管理方式,它提供高分辨率的横断面成像,有助于早期检测和持续监测。然而,传统的OCT设备仅限于临床环境,需要技术人员操作,这带来了一些可及性挑战,比如预约困难、患者及其家属频繁就医的交通负担,以及医疗成本增加,尤其是在可治疗的病变未被检测到的情况下。随着年龄相关性黄斑变性(AMD)和糖尿病视网膜病变等视网膜疾病在全球的负担日益加重,迫切需要提高视网膜疾病检测的可及性。生物医学工程的进步带来了诸如便携式设备、基于社区的系统以及人工智能辅助图像分析等创新成果。SightSync OCT是一种基于社区的、无需技术人员操作的设备,旨在提高可及性,同时确保安全的数据传输和高质量成像(分辨率为6×6毫米,每秒80,000次A扫描)。凭借其紧凑的设计和远程解读的潜力,SightSync拓宽了基于社区筛查威胁视力的视网膜疾病的可能性。通过整合OCT成像方面的创新成果,视网膜疾病监测的未来有望得到改变,以减少就医障碍并改善患者预后。本文讨论了OCT技术的发展历程、其在视网膜疾病诊断和管理中的作用,以及像SightSync OCT这样的新型工程解决方案如何改变视网膜成像的可及性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6377/12108957/736b0a1f6a10/bioengineering-12-00441-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6377/12108957/6d0a55449a6e/bioengineering-12-00441-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6377/12108957/d113339bf74e/bioengineering-12-00441-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6377/12108957/72185b8ee109/bioengineering-12-00441-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6377/12108957/736b0a1f6a10/bioengineering-12-00441-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6377/12108957/6d0a55449a6e/bioengineering-12-00441-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6377/12108957/d113339bf74e/bioengineering-12-00441-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6377/12108957/72185b8ee109/bioengineering-12-00441-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6377/12108957/736b0a1f6a10/bioengineering-12-00441-g004.jpg

相似文献

[1]
Recent Optical Coherence Tomography (OCT) Innovations for Increased Accessibility and Remote Surveillance.

Bioengineering (Basel). 2025-4-23

[2]
Optical coherence tomography for age-related macular degeneration and diabetic macular edema: an evidence-based analysis.

Ont Health Technol Assess Ser. 2009

[3]
High-definition and 3-dimensional imaging of macular pathologies with high-speed ultrahigh-resolution optical coherence tomography.

Ophthalmology. 2006-11

[4]
Optical coherence tomography--current and future applications.

Curr Opin Ophthalmol. 2013-5

[5]
Evaluation of a Remote Diagnosis Imaging Model vs Dilated Eye Examination in Referable Macular Degeneration.

JAMA Ophthalmol. 2019-7-1

[6]
Evaluation of an Artificial Intelligence-Based Detector of Sub- and Intraretinal Fluid on a Large Set of Optical Coherence Tomography Volumes in Age-Related Macular Degeneration and Diabetic Macular Edema.

Ophthalmologica. 2022

[7]
Optical coherence tomography (OCT) for detection of macular oedema in patients with diabetic retinopathy.

Cochrane Database Syst Rev. 2015-1-7

[8]
Advancing Diabetic Retinopathy Diagnosis: Leveraging Optical Coherence Tomography Imaging with Convolutional Neural Networks.

Rom J Ophthalmol. 2023

[9]
Self-examination low-cost full-field OCT (SELFF-OCT) for patients with various macular diseases.

Graefes Arch Clin Exp Ophthalmol. 2021-6

[10]
Reliability of Retinal Layer Annotation with a Novel, High-Resolution Optical Coherence Tomography Device: A Comparative Study.

Bioengineering (Basel). 2023-3-31

本文引用的文献

[1]
Validation of Deep Learning-Based Automatic Retinal Layer Segmentation Algorithms for Age-Related Macular Degeneration with 2 Spectral-Domain OCT Devices.

Ophthalmol Sci. 2024-12-4

[2]
Development of next generation low-cost OCT towards improved point-of-care retinal imaging.

Biomed Opt Express. 2025-1-30

[3]
Retinal thickness predicts the risk of cognitive decline over five years.

Alzheimers Res Ther. 2024-12-23

[4]
Global burden of low vision and blindness due to age-related macular degeneration from 1990 to 2021 and projections for 2050.

BMC Public Health. 2024-12-18

[5]
Anti-VEGF treatment outcome prediction based on optical coherence tomography images in neovascular age-related macular degeneration using a deep neural network.

Sci Rep. 2024-11-16

[6]
Home-monitoring/remote optical coherence tomography in teleophthalmology in patients with eye disorders-a systematic review.

Front Med (Lausanne). 2024-10-24

[7]
Developing a 10-Layer Retinal Segmentation for MacTel Using Semi-Supervised Learning.

Transl Vis Sci Technol. 2024-11-4

[8]
Precision Segmentation of Subretinal Fluids in OCT Using Multiscale Attention-Based U-Net Architecture.

Bioengineering (Basel). 2024-10-16

[9]
Optical coherence tomography angiography of the retina and choroid in systemic diseases.

Prog Retin Eye Res. 2024-11

[10]
A Comprehensive Review of Ocular Manifestations in Systemic Diseases.

Cureus. 2024-7-29

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