Otsuka Hikaru, Tabata Hiroki, Shi Huicong, Kaga Hideyoshi, Someya Yuki, Abulaiti Abudurezake, Naito Hitoshi, Umemura Futaba, Kakehi Saori, Ishijima Muneaki, Kawamori Ryuzo, Watada Hirotaka, Tamura Yoshifumi
Department of Sports Medicine and Sportology, Graduate School of Medicine, Juntendo University, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421, Japan.
Sportology Center, Graduate School of Medicine, Juntendo University, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421, Japan.
J Clin Med. 2021 Dec 19;10(24):5968. doi: 10.3390/jcm10245968.
We investigated effects of exercise habits (EHs) in adolescence and old age on osteoporosis prevalence and hip joint and lumbar spine bone mineral density (BMD). Body composition and BMD in 1596 people aged 65-84 years living in Bunkyo-ku, Tokyo, were measured using dual-energy X-ray absorptiometry. We divided participants into four groups by a combination of EHs in adolescence and old age: none in either period (None-None), only in adolescence (Active-None), only in old age (None-Active), and in both periods (Active-Active). Logistic regression models were employed to estimate multivariable-adjusted odds ratios (ORs) for osteoporosis determined by T-score (less than -2.5 SD) using the None-None reference group. In men, the combination of EHs in adolescence and old age was not associated with osteoporosis prevalence. However, the lumbar spine's BMD was significantly higher in the Active-Active than the None-Active group ( = 0.043). In women, the Active-Active group had lower lumbar spine osteoporosis prevalence than the None-None group (OR 0.65; 95% CI, 0.42-1.00, = 0.049). Furthermore, hip BMD was significantly higher in the Active-Active group than in the other three groups ( = 0.001). Older women with EHs in adolescence and old age had higher lumbar BMD and lower risk of osteoporosis.
我们研究了青少年期和老年期的运动习惯对骨质疏松症患病率以及髋关节和腰椎骨密度（BMD）的影响。使用双能X线吸收法测量了居住在东京文京区的1596名65 - 84岁人群的身体成分和骨密度。我们根据青少年期和老年期的运动习惯组合将参与者分为四组：两个时期均无运动习惯（无-无）、仅青少年期有运动习惯（活跃-无）、仅老年期有运动习惯（无-活跃）以及两个时期均有运动习惯（活跃-活跃）。采用逻辑回归模型，以无-无组为参照，估计由T评分（低于-2.5标准差）确定的骨质疏松症的多变量调整比值比（OR）。在男性中，青少年期和老年期的运动习惯组合与骨质疏松症患病率无关。然而，活跃-活跃组的腰椎骨密度显著高于无-活跃组（P = 0.043）。在女性中，活跃-活跃组的腰椎骨质疏松症患病率低于无-无组（OR 0.65；95%可信区间，0.42 - 1.00，P = 0.049）。此外，活跃-活跃组的髋部骨密度显著高于其他三组（P = 0.001）。青少年期和老年期有运动习惯的老年女性腰椎骨密度更高，骨质疏松症风险更低。
