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老年期骨密度:初潮年龄、绝经状态以及过去和现在的习惯性身体活动的影响。

Bone mineral density in old age: the influence of age at menarche, menopause status and habitual past and present physical activity.

作者信息

Kopiczko Anna

机构信息

Department of Anthropology and Health Promotion, Faculty of Biomedical Sciences, Józef Piłsudski University of Physical Education, Warsaw, Poland.

出版信息

Arch Med Sci. 2019 Jan 15;16(3):657-665. doi: 10.5114/aoms.2019.81314. eCollection 2020.

DOI:10.5114/aoms.2019.81314
PMID:32399115
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7212225/
Abstract

INTRODUCTION

In this study, the hypothesis that bone mineral density (BMD) of peri-, pre- and postmenopausal women is associated with the current level of habitual physical activity, as well as past physical activity, at the age of building peak bone mass, was tested.

MATERIAL AND METHODS

The study involved 500 Polish women aged 40 to 70. For the assessment of BMD and bone mineral content (BMC) the densitometry method (dual-energy X-ray absorptiometry, DXA) of the forearm bone was used. The International Physical Activity Questionnaire (IPAQ) was used to assess the present level of physical activity. The assessment of past physical activity was related to adolescence.

RESULTS

There was a significant, strong influence on the norm BMD in the distal forearm sections values in the distal forearm sections of such variables as: older age of the first menstruation (OR = 1.37; = 0.002), sufficient present physical activity (OR = 1.57; = 0.001), and particularly high past physical activity (OR = 6.77; = 0.003). Significantly lower chances for the norm BMD dis were found in women with the oldest hormonal status (OR = 0.09; < 0.001). In the proximal segment, the analogous conditions of the norm BMD, and in addition the chances for good mineralization, were increased by higher body mass index (OR = 1.11; < 0.001). Sufficient present activity increased the chances of good forearm mineralization in the proximal part more than four times (OR = 4.2; < 0.001), and a high level of past physical activity increased these chances several dozen times (OR = 69.9; < 0.001).

CONCLUSIONS

Physical activity proved to be one of the most important factors determining the statistically significant correct mineralization of bone tissue of women.

摘要

引言

在本研究中,对绝经前后及绝经后女性的骨矿物质密度(BMD)与当前习惯性身体活动水平以及在骨量峰值形成年龄时的既往身体活动相关这一假设进行了检验。

材料与方法

该研究纳入了500名年龄在40至70岁之间的波兰女性。采用前臂骨密度测量法(双能X线吸收法,DXA)评估骨矿物质密度(BMD)和骨矿物质含量(BMC)。使用国际身体活动问卷(IPAQ)评估当前身体活动水平。既往身体活动的评估与青春期相关。

结果

以下变量对前臂远端部分的正常骨密度有显著且强烈的影响:初潮年龄较大(比值比[OR]=1.37;P=0.002)、当前身体活动充足(OR=1.57;P=0.001),尤其是既往身体活动水平较高(OR=6.77;P=0.003)。在激素状态最年长的女性中,正常骨密度的几率显著降低(OR=0.09;P<0.001)。在近端部分,较高的体重指数增加了正常骨密度以及良好矿化的几率(OR=1.11;P<0.001)。当前充足的活动使近端前臂良好矿化的几率增加了四倍多(OR=4.2;P<0.001),而高水平的既往身体活动使这些几率增加了几十倍(OR=69.9;P<0.001)。

结论

身体活动被证明是决定女性骨组织统计学上显著正确矿化的最重要因素之一。

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