Seymour C B, Mothersill C
Int J Radiat Biol Relat Stud Phys Chem Med. 1987 Mar;51(3):381-91. doi: 10.1080/09553008714550881.
When differentiated 15-day-old cultures of human thyroid glands were irradiated they exhibited a high degree of radiosensitivity, an absence of split-dose recovery, an increase in the number of non-senescent colonies observed over four passages, increased focus formation on the confluent postirradiation monolayer and a shift in the isozyme pattern of LDH towards the anaerobic form (LD 5). The effects are similar to those previously observed for irradiated sheep thyroid cultures, but occurred at lower radiation doses.
当对培养15天的人甲状腺分化细胞进行照射时，它们表现出高度的放射敏感性，不存在分次照射恢复现象，在四代培养中观察到非衰老集落数量增加，辐照后汇合单层上的集落形成增加，以及乳酸脱氢酶同工酶模式向厌氧形式（LD 5）转变。这些效应与先前在辐照绵羊甲状腺培养物中观察到的效应相似，但在较低辐射剂量下就会出现。
