Bioorganic and Biophysical Chemistry Laboratory, Linnaeus Centre for Biomaterials Chemistry, Department of Chemistry and Biomedical Sciences, Linnaeus University, 39231, Kalmar, Sweden.
Sci Rep. 2021 Dec 24;11(1):24420. doi: 10.1038/s41598-021-04001-4.
Nano-structured materials are used in electronics, diagnostics, therapeutics, smart packaging, energy management and textiles, areas critical for society and quality of life. However, their fabrication often places high demands on limited natural resources. Accordingly, renewable sources for the feedstocks used in their production are highly desirable. We demonstrate the use of readily available biopolymers derived from maize (zein), milk (casein) and malacostraca (crab-shell derived chitin) in conjunction with sacrificial templates, self-assembled monodisperse latex beads and anodized aluminium membranes, for producing robust surfaces coated with highly regular hyperporous networks or wire-like morphological features, respectively. The utility of this facile strategy for nano-structuring of biopolymers was demonstrated in a surface based-sensing application, where biotin-selective binding sites were generated in the zein-based nano-structured hyperporous network.
纳米结构材料在电子、诊断、治疗、智能包装、能源管理和纺织品等领域得到了广泛应用，这些领域对社会和生活质量至关重要。然而，它们的制造通常对有限的自然资源提出了很高的要求。因此，人们非常希望使用可再生资源作为生产这些材料的原料。我们展示了如何使用玉米（玉米醇溶蛋白）、牛奶（酪蛋白）和软甲纲动物（蟹壳衍生的壳聚糖）等易于获得的生物聚合物，结合牺牲模板、自组装单分散乳胶珠和阳极氧化铝膜，分别制备出具有高度规则的超多孔网络或线状形态特征的涂覆有刚性表面的聚合物。在基于表面的传感应用中，我们展示了这种简单策略在生物聚合物纳米结构化方面的应用，其中在玉米醇溶蛋白基的超多孔网络中生成了生物素选择性结合位点。
