Manzano Miguel
Chemistry in Pharmaceutical Sciences, School of Pharmacy, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria Hospital 12 de Octubre i + 12, Plaza de Ramón y Cajal s/n, E-28040 Madrid, Spain.
Networking Research Centre on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), E-28034 Madrid, Spain.
Pharmaceutics. 2021 Dec 17;13(12):2179. doi: 10.3390/pharmaceutics13122179.
Twenty years ago, a group of bold scientists led by Prof Vallet-Regí suggested for the first time the use of mesoporous materials as potential drug delivery systems. Without knowing it; these pioneers unleashed the beast of creativity around the world because that original idea has been the inspiration of hundreds of scientific groups for the design of many versatile delivery systems based on mesoporous materials. Because the dream is not the destination, it is the journey, the present review aims to summarise the chain of events that catapulted a small and young research team from the grassroots of academia to the elite of the Biomedical Engineering field.
二十年前,由瓦列特 - 雷吉教授领导的一群勇敢的科学家首次提出将介孔材料用作潜在的药物递送系统。当时他们并未意识到,这些先驱者在全球范围内释放了创造力的猛兽,因为那个最初的想法激发了数百个科学团队的灵感,促使他们设计出许多基于介孔材料的多功能递送系统。因为梦想不是终点,而是旅程,本综述旨在总结一系列事件,这些事件将一个年轻的小型研究团队从学术界的基层推向了生物医学工程领域的精英行列。