Department of Surgery, Division of Gastroenterological, General and Transplant Surgery, Jichi Medical University, Shimotsuke-City 329-0498, Japan.
Division of Community and Family Medicine, Jichi Medical University, Shimotsuke-City 329-0498, Japan.
Nutrients. 2021 Dec 8;13(12):4394. doi: 10.3390/nu13124394.
Previous systematic reviews have not clarified the effect of postoperative coffee consumption on the incidence of postoperative ileus (POI) and the length of hospital stay (LOS). We aimed to assess its effect on these postoperative outcomes.
Studies evaluating postoperative coffee consumption were searched using electronic databases until September 2021 to perform random-effect meta-analysis. The quality of evidence was assessed using the Cochrane risk-of-bias tool. Caffeinated and decaffeinated coffee were also compared.
Thirteen trials (1246 patients) and nine ongoing trials were included. Of the 13 trials, 6 were on colorectal surgery, 5 on caesarean section, and 2 on gynecological surgery. Coffee reduced the time to first defecation (mean difference (MD) -10.1 min; 95% confidence interval (CI) = -14.5 to -5.6), POI (risk ratio 0.42; 95% CI = 0.26 to 0.69); and LOS (MD -1.5; 95% CI = -2.7 to -0.3). This trend was similar in colorectal and gynecological surgeries. Coffee had no adverse effects. There was no difference in POI or LOS between caffeinated and decaffeinated coffee ( > 0.05). The certainty of evidence was low to moderate.
This review showed that postoperative coffee consumption, regardless of caffeine content, likely reduces POI and LOS after colorectal and gynecological surgery.
先前的系统评价并未阐明术后饮用咖啡对术后肠梗阻（POI）发生率和住院时间（LOS）的影响。我们旨在评估其对这些术后结果的影响。
使用电子数据库搜索评估术后咖啡消耗的研究，直到 2021 年 9 月进行随机效应荟萃分析。使用 Cochrane 偏倚风险工具评估证据质量。还比较了含咖啡因和不含咖啡因的咖啡。
纳入了 13 项试验（1246 名患者）和 9 项正在进行的试验。在这 13 项试验中，6 项是结直肠手术，5 项是剖宫产，2 项是妇科手术。咖啡可减少首次排便时间（平均差值（MD）-10.1 分钟；95%置信区间（CI）=-14.5 至-5.6）、POI（风险比 0.42；95%CI=0.26 至 0.69）和 LOS（MD-1.5；95%CI=-2.7 至-0.3）。这种趋势在结直肠和妇科手术中相似。咖啡没有不良反应。含咖啡因和不含咖啡因的咖啡在 POI 或 LOS 方面没有差异（>0.05）。证据的确定性为低至中度。
本综述表明，无论含咖啡因与否，术后饮用咖啡可能会减少结直肠和妇科手术后的 POI 和 LOS。
