First Department of Surgery, General Hospital of Attica "KAT", Athens, Greece,
First Department of Surgery, General Hospital of Attica "KAT", Athens, Greece.
Dig Surg. 2020;37(1):22-31. doi: 10.1159/000496431. Epub 2019 Jan 11.
Postoperative ileus prolongs both hospital stay and patients' morbidity, having at the same time a great impact on health care costs. Coffee, a worldwide popular, cheap beverage might have an important effect on the motility of the postoperative bowel.
PubMed, Scopus, and Cochrane Central Register of Controlled Trials were systematically searched.
Four studies met the inclusion criteria of our meta-analysis. A total of 341 patients were included. The postoperative administration of coffee significantly reduces the time to first bowel movement, the time to first flatus and the time to tolerance of solid diet. Safe conclusions could not be drawn regarding the additional use of laxatives, the necessity for reinsertion of nasogastric tube or the need for reoperation as all the aforementioned outcomes did not present any statistically significance. None of the complications were attributed to the administration of coffee.
The administration of coffee as a postoperative ileus prevention measure can change the way postoperative enhanced recovery is applied. Even though the mechanism of action of coffee is not fully known, currently available literature demonstrates a significant improvement in gastrointestinal motility without having any impact on postoperative morbidity. Studies with higher methodological quality can offer a more careful evaluation of the clinical use of this popular beverage.
术后肠麻痹既延长了住院时间，又增加了患者的发病率，同时对医疗保健成本也有重大影响。咖啡作为一种全球流行的廉价饮料，可能对术后肠道蠕动有重要影响。
系统检索了 PubMed、Scopus 和 Cochrane 对照试验中心注册库。
四项研究符合我们的荟萃分析纳入标准。共有 341 名患者纳入研究。术后给予咖啡可显著减少首次排气、首次排便和耐受固体饮食的时间。但由于所有上述结局均无统计学意义，因此不能得出关于额外使用泻药、是否需要重新插入鼻胃管或是否需要再次手术的安全结论。咖啡的使用未引起任何并发症。
将咖啡作为预防术后肠麻痹的措施，可以改变术后加速康复的应用方式。尽管咖啡的作用机制尚未完全明确，但现有文献表明，咖啡可显著改善胃肠道蠕动，而不会对术后发病率产生影响。更高质量的研究可以更仔细地评估这种受欢迎的饮料的临床应用。
