Gunasekaran Venugopalan, Subramanian Manicka Saravanan, Singh Vishwajeet, Dey Aparajit Ballav
Department of Geriatric Medicine All India Institute of Medical Sciences New Delhi India.
Department of Geriatric Medicine Jawaharlal Institute of Postgraduate Medical Education and Research Puducherry India.
Aging Med (Milton). 2021 Nov 12;4(4):266-271. doi: 10.1002/agm2.12181. eCollection 2021 Dec.
The integral part of the definition of frailty is the outcome associated with it. Older adults at risk of frailty are in the process of becoming frail. This study looked at the clinical characteristics and outcomes of older adults at risk of frailty.
The study population was selected from outpatient department of the geriatric medicine department in a tertiary care hospital. Older adults identified as at risk of frailty were assessed at baseline and then followed up after 1 year for the composite primary outcome of death, falls, hospitalization, and self-rated poor quality of life in the follow-up period.
The study included 324 older adults who had completed 1-year follow up. Mean (SD) age was 74.49 (4.58) years, and males were 241 (74.15%). Frail and pre-frail at baseline among the study population were 31.17% and 61.11%, respectively. The primary outcome occurred in 43 (13.27%) patients. Poor baseline IADL was significantly associated with primary outcome at the end of 1 year.
An unfavorable outcome in older adults at risk of frailty was significantly higher and independent of their baseline frailty status. Poor baseline IADL value may be considered as a predictor for primary outcome at 1 year of follow up.
衰弱定义的核心部分是与之相关的结果。有衰弱风险的老年人正处于逐渐衰弱的过程中。本研究观察了有衰弱风险的老年人的临床特征和结果。
研究人群选自一家三级医院老年医学科门诊。被确定为有衰弱风险的老年人在基线时接受评估，然后在1年后进行随访，观察随访期间死亡、跌倒、住院和自评生活质量差的综合主要结局。
该研究纳入了324名完成1年随访的老年人。平均（标准差）年龄为74.49（4.58）岁，男性241人（74.15%）。研究人群中基线时衰弱和衰弱前期分别为31.17%和61.11%。43名（13.27%）患者出现了主要结局。基线时工具性日常生活活动能力差与1年末的主要结局显著相关。
有衰弱风险的老年人不良结局显著更高，且独立于其基线衰弱状态。基线工具性日常生活活动能力差的值可被视为1年随访时主要结局的预测指标。
