State Institution «Institute of Urology of the National Academy of Medical Sciences of Ukraine», 9a, Volodymyra Vynnychenka St., Kyiv, 04053, Ukraine.
Probl Radiac Med Radiobiol. 2021 Dec;26:479-497. doi: 10.33145/2304-8336-2021-26-479-497.
The article attempts to analyze the nature of sexual dysfunctions in patients living in areas exposed toionizing radiation as a result of the Chornobyl accident.
A study of sexual function was carried out in 186 people (group I) living in the territoriesof Kyiv (Polisske, Chornobyl, Ivankiv, Borodianka, Vyshhorod, Makariv districts) and Zhytomyr (Malyn and Korostendistricts) regions. The control group consisted of persons who were born and lived on the territory of Ivano-Frankivsk and Chernivtsi regions (group II, n = 123). Diagnostics was carried out on an outpatient basis in accor-dance with the standards of the WHO and the Ministry of Health of Ukraine.
Analyzing the obtained research results, a significantly larger number of patients with sexual dysfunctionwas identified in group I (82.3 %) than in group II (44.7 %) (р < 0.01). Psychopathological disorders disturbed,respectively, 60.2 % and 41.4 % (p < 0.01). Complaints of decreased libido were presented by 25.8 % of the surveyedmen exposed to ionizing radiation, and 6.5 % of them were concerned about a sharp depression of libido. In groupII patients, this indicator was 14.6 % and 3.3 %, respectively. The integral index of «libido» of the ICEF question-naire revealed a statistically significant difference between the groups (9.23 ± 0.89 and 12.22 ± 1.26, respectively;р < 0.05). In patients exposed to ionizing radiation as a result of the Chornobyl accident, the concentration oftestosterone decreases, and the content of FSH, LH, as well as globulin, which makes sex hormones, increases.Erectile dysfunction in patients of group I was detected in 58.1 % of men, and in patients of group II - 35.0 % (р < 0.01).The difference in the integral indicators of the ICEF questionnaire between the groups was 1.3 times behind the«libido» domain. For other domains - by 1.5-1.6 times. In men living in the territories of Kyiv and Zhytomyr regions,erectile dysfunction occurs earlier and is characterized by a more severe course than in people born and lived in theterritory of Ivano-Frankivsk and Chernivtsi regions. Both in terms of low rates of normal erection (in patients ofgroups I and II, respectively 3.8 % and 13.3 %), and for high percentages of existing moderate/severe ED (respec-tively 71.0 % and 45.5 %), persons from group I are characterized by significantly worse data than persons fromgroup II (р < 0.01). Orgasm pathology was found in 40.3 % of patients in group I and in 25.2 % of patients in groupII (р < 0.01). The quality of life index according to the QoL index in the context of existing sexual disorders in groupI of patients was 4.7 ± 0.4, in patients of group II - 3.9 ± 0.2 (р < 0.05).
The data obtained indicate a tendency for a more significant violation of sexual functions in men whowere born and lived in territories exposed to radioactive contamination as a result of the Chornobyl accident.
本文试图分析因切尔诺贝利事故而暴露在电离辐射下的患者的性功能障碍的性质。
对生活在基辅地区（Polisske、Chornobyl、Ivankiv、Borodianka、Vyshhorod、Makariv 区）和日托米尔地区（Malyn 和 Korosten 区）的 186 人（I 组）进行了性功能研究。对照组由出生和居住在伊万诺-弗兰科夫斯克和切尔诺夫策地区的人组成（II 组，n=123）。根据世界卫生组织和乌克兰卫生部的标准，进行了门诊诊断。
分析获得的研究结果，I 组（82.3%）中性功能障碍患者的数量明显多于 II 组（44.7%）（р < 0.01）。心理病理障碍分别干扰了 60.2%和 41.4%的患者（р < 0.01）。25.8%暴露于电离辐射的调查男性抱怨性欲减退，其中 6.5%的人对性欲明显减退感到担忧。在 II 组患者中，这一指标分别为 14.6%和 3.3%。ICEF 问卷的“性欲”综合指数显示两组之间存在统计学差异（分别为 9.23±0.89 和 12.22±1.26；р < 0.05）。因切尔诺贝利事故而暴露于电离辐射的患者中，睾丸激素浓度降低，促卵泡激素、黄体生成素以及使性激素球蛋白的含量增加。I 组患者中 58.1%的男性存在勃起功能障碍，而 II 组患者中 35.0%（р < 0.01）。两组之间 ICEF 问卷的综合指标差异落后于“性欲”域 1.3 倍。对于其他域，则落后 1.5-1.6 倍。居住在基辅和日托米尔地区的男性，勃起功能障碍出现得更早，且比出生和居住在伊万诺-弗兰科夫斯克和切尔诺夫策地区的男性更为严重。无论是低正常勃起率（I 组和 II 组患者分别为 3.8%和 13.3%），还是存在中度/重度 ED 的高比例（分别为 71.0%和 45.5%），I 组患者的情况均明显差于 II 组患者（р < 0.01）。I 组患者中有 40.3%存在射精障碍，而 II 组患者中有 25.2%（р < 0.01）。在 I 组患者中，存在性障碍的生活质量指数根据 QoL 指数为 4.7±0.4，在 II 组患者中为 3.9±0.2（р < 0.05）。
所得数据表明，因切尔诺贝利事故而暴露在放射性污染下的男性中，性功能障碍更明显。
