Jenkins Herman A, Greene Nathaniel, Tollin Daniel J
Department of Otolaryngology-Head and Neck Surgery, University of Colorado School of Medicine, Aurora, CO, United States.
Department of Physiology and Biophysics, University of Colorado School of Medicine, Aurora, CO, United States.
Front Neurol. 2021 Dec 14;12:777010. doi: 10.3389/fneur.2021.777010. eCollection 2021.
Mixed hearing loss associated with a sensorineural component and an impaired conductive mechanism for sound from the external ear canal to the cochlea represents a challenge for rehabilitation using either surgery or traditional hearing amplification. Direct stimulations of the ossicular chain and the round window (RW) membrane have allowed an improved hearing in this population. The authors review the developments in basic and clinical research that have allowed the exploration of new routes for inner ear stimulation. Similar changes occur in the electrophysiological measures in response to auditory stimulation through the traditional route and direct mechanical stimulation of the RW. The latter has proven to be very effective as a means of hearing rehabilitation in a group of patients with significant difficulties with hearing and communication.
混合性听力损失伴有感音神经性成分以及从外耳道到耳蜗的声音传导机制受损，这对采用手术或传统听力放大进行康复治疗构成了挑战。对听骨链和圆窗（RW）膜的直接刺激已使该人群的听力得到改善。作者回顾了基础和临床研究的进展，这些进展使得探索内耳刺激的新途径成为可能。通过传统途径进行听觉刺激以及对RW进行直接机械刺激时，电生理测量会出现类似变化。事实证明，后者作为一种听力康复手段，对一组听力和沟通存在严重困难的患者非常有效。
