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低地球轨道的再生医学生物制造。

Biomanufacturing in low Earth orbit for regenerative medicine.

机构信息

Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA; Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA; Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, USA.

Axiom Space, Inc., Houston, TX, USA.

出版信息

Stem Cell Reports. 2022 Jan 11;17(1):1-13. doi: 10.1016/j.stemcr.2021.12.001. Epub 2021 Dec 30.

Abstract

Research in low Earth orbit (LEO) has become more accessible. The 2020 Biomanufacturing in Space Symposium reviewed space-based regenerative medicine research and discussed leveraging LEO to advance biomanufacturing for regenerative medicine applications. The symposium identified areas where financial investments could stimulate advancements overcoming technical barriers. Opportunities in disease modeling, stem-cell-derived products, and biofabrication were highlighted. The symposium will initiate a roadmap to a sustainable market for regenerative medicine biomanufacturing in space. This perspective summarizes the 2020 Biomanufacturing in Space Symposium, highlights key biomanufacturing opportunities in LEO, and lays the framework for a roadmap to regenerative medicine biomanufacturing in space.

摘要

低地球轨道(LEO)的研究变得更加容易。2020 年太空生物制造研讨会回顾了基于太空的再生医学研究,并讨论了利用 LEO 推进再生医学应用的生物制造。该研讨会确定了可以通过财务投资来刺激克服技术障碍的领域。疾病建模、干细胞衍生产品和生物制造方面的机会得到了强调。研讨会将启动太空再生医学生物制造可持续市场的路线图。本观点总结了 2020 年太空生物制造研讨会,强调了 LEO 中的关键生物制造机会,并为太空再生医学生物制造的路线图奠定了框架。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13b9/8758939/c8e6079ae2c5/gr1.jpg

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