Clark A J, Mossholder S, Gates R
Am J Clin Nutr. 1987 Aug;46(2):302-6. doi: 10.1093/ajcn/46.2.302.
The folacin status of 103 adolescent females aged 12, 14, and 16 y was evaluated. In the third year, longitudinal data regarding folacin status was obtained from 50 girls aged 14 and 16 y who had participated in the first year. In the first year, 11.7% and 47.6% of the girls had serum and erythrocyte folacin levels less than 3 ng/mL (6.8 nmol/L) and 140 ng/mL (317 nmol/L), respectively. Serum folacin levels and dietary folacin intake decreased with increasing age but not significantly. During the first year, 75% and 66% of the subjects that were folacin deficient based upon serum and erythrocyte folacin values, respectively, were the same subjects considered to be deficient during the third year. Folacin status, as indicated by serum and erythrocyte folacin values, was not related to per capita income. These findings demonstrate that folacin status is less than adequate in females during the adolescent years.
对103名年龄在12岁、14岁和16岁的青春期女性的叶酸状况进行了评估。在第三年，从第一年参与研究的50名14岁和16岁女孩那里获得了关于叶酸状况的纵向数据。在第一年，分别有11.7%和47.6%的女孩血清和红细胞叶酸水平低于3 ng/mL（6.8 nmol/L）和140 ng/mL（317 nmol/L）。血清叶酸水平和膳食叶酸摄入量随年龄增长而下降，但不显著。在第一年，分别根据血清和红细胞叶酸值判定为叶酸缺乏的受试者中，75%和66%在第三年仍被认为是缺乏者。血清和红细胞叶酸值表明的叶酸状况与人均收入无关。这些发现表明，青春期女性的叶酸状况不太理想。
