Bailey L B, Wagner P A, Christakis G J, Davis C G, Appledorf H, Araujo P E, Dorsey E, Dinning J S
Am J Clin Nutr. 1982 May;35(5):1023-32. doi: 10.1093/ajcn/35.5.1023.
The folacin and iron status of 193 adolescents from urban low-income households was evaluated. Red blood cell folacin concentrations were less than 140 ng/ml in 42% of the subjects and 140 to 159 ng/ml in 13%. Of the serum folacin values, 45% were less than 6 ng/ml, and 15% were below 3 ng/ml. Serum folacin levels decreased with increasing age (p less than 0.01) and sexual maturity (p less than 0.05). Transferrin saturation was low (less than 16%) in 12% of the females and 2% of the males. Transferrin saturation levels for females declined as age increased in contrast to an increase over age in males (p less than 0.01). Eleven percent of the females and 3% of the males were classified as anemic (less than 12 g/dl). Mean cell Hb concentration was low (less than 32%) in 24% of the females and 7% of the males. Of all subjects, 17% had low mean cell volumes (less than 81 mum 3). These findings demonstrate folacin and iron status is less than adequate in a significant proportion of this adolescent population group.
对193名来自城市低收入家庭的青少年的叶酸和铁状况进行了评估。42%的受试者红细胞叶酸浓度低于140 ng/ml,13%的受试者红细胞叶酸浓度为140至159 ng/ml。血清叶酸值中,45%低于6 ng/ml,15%低于3 ng/ml。血清叶酸水平随年龄增长(p<0.01)和性成熟度增加(p<0.05)而降低。12%的女性和2%的男性转铁蛋白饱和度较低(低于16%)。与男性随年龄增加而升高相反,女性的转铁蛋白饱和度水平随年龄增加而下降(p<0.01)。11%的女性和3%的男性被归类为贫血(血红蛋白低于12 g/dl)。24%的女性和7%的男性平均红细胞血红蛋白浓度较低(低于32%)。在所有受试者中,17%的人平均红细胞体积较低(低于81μm³)。这些发现表明,在这一青少年人群中,相当一部分人的叶酸和铁状况不足。