Bailey L B, Wagner P A, Christakis G J, Araujo P E, Appledorf H, Davis C G, Masteryanni J, Dinning J S
Am J Clin Nutr. 1979 Nov;32(11):2346-53. doi: 10.1093/ajcn/32.11.2346.
The folacin and iron status and hemotological parameters of 193 persons 60 years of age and older from urban low-income households were evaluated. Of the serum folacin values 30% were between 3 and 6 ng/ml and 8% were below 3 ng/ml. Of these subjects 60% could be classified as "high risk" (less than 140 ng/ml) and 11% as "medium risk" (140 to 160 ng/ml) based on red blood cell folacin concentrations. Serum iron was normal (greater than 50 micrograms/dl) for all subjects as was transferrin saturation (greater than 15%). Hematological indices showed a 14% incidence of anemia (hemaglobin less than 12 g/dl), and 32% incidence of leukopenia (leukocytes less than 4.8 X 10(3)). These findings demonstrate widespread folacin deficiency and no evidence of iron deficiency in these elderly people.
对193名来自城市低收入家庭的60岁及以上老人的叶酸和铁状况以及血液学参数进行了评估。血清叶酸值中，30%在3至6纳克/毫升之间，8%低于3纳克/毫升。根据红细胞叶酸浓度，这些受试者中60%可归类为“高风险”（低于140纳克/毫升），11%为“中度风险”（140至160纳克/毫升）。所有受试者的血清铁均正常（大于50微克/分升），转铁蛋白饱和度也正常（大于15%）。血液学指标显示贫血发生率为14%（血红蛋白低于12克/分升），白细胞减少症发生率为32%（白细胞低于4.8×10³）。这些发现表明这些老年人中存在广泛的叶酸缺乏，且无缺铁证据。
