Bogari Anas A, Alsolami Basel M, Al-Husayni Faisal, Munshi Adeeb, Alharbi Maher
Internal Medicine, National Guard Hospital, Jeddah, SAU.
Internal Medicine, King Saud Bin Abdulaziz University for Health Sciences, College of Medicine-Western Region, Jeddah, SAU.
Cureus. 2021 Nov 24;13(11):e19853. doi: 10.7759/cureus.19853. eCollection 2021 Nov.
Non-O1, non-O139 (NOVC) are considered non-pathogenic organisms, but in some cases, it is known to be responsible for self-limiting intestinal and extra-intestinal infections in immunocompetent individuals. On the other hand, NOVC bacteremia affects mainly immunocompromised patients with significantly high mortality rates. We report a case of an 80-year-old female with a 20-year history of multiple abdominal surgeries. She is also known to have ischemic heart disease and atrial fibrillation. The patient presented with abdominal pain and signs of septic shock. Her abdominal imaging showed features of ascending cholangitis, while her blood culture grew . She was discharged after completing the course of antibiotics but then came back with a similar presentation. The repeated blood culture showed , while other cultures were negative. The patient's condition worsened due to sepsis, and she passed away. NOVC bacteremia is a fatal disease even in hosts who are not receiving immunosuppressants or chemotherapy. It may present without a history of diarrhea or seafood ingestion. In such situations, abdominal imaging is necessary to identify the presence of intra-abdominal infections.
非O1、非O139（NOVC）被认为是非致病生物体，但在某些情况下，已知其会导致免疫功能正常个体发生自限性肠道和肠道外感染。另一方面，NOVC菌血症主要影响免疫功能低下的患者，死亡率显著较高。我们报告一例80岁女性病例，该患者有20年多次腹部手术史。她还患有缺血性心脏病和心房颤动。患者出现腹痛和感染性休克体征。她的腹部影像学显示有化脓性胆管炎特征，而血培养培养出……。她在完成抗生素疗程后出院，但随后又以类似症状复诊。再次血培养培养出……，而其他培养结果均为阴性。患者因败血症病情恶化，最终去世。即使在未接受免疫抑制剂或化疗的宿主中，NOVC菌血症也是一种致命疾病。它可能在没有腹泻或食用海鲜史的情况下出现。在这种情况下，需要进行腹部影像学检查以确定是否存在腹腔内感染。
