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不同微创术式治疗颈椎病后生物力学特性的比较分析:有限元分析

Comparative Analysis of the Biomechanical Characteristics After Different Minimally Invasive Surgeries for Cervical Spondylopathy: A Finite Element Analysis.

作者信息

He Tao, Zhang Jun, Yu Tong, Wu Jiuping, Yuan Tianyang, Liu Rui, Yun Zhihe, Du Haorui, Qi Le, An Junyan, Xue Wu, Nie Xinyu, Liu Qinyi

机构信息

Department of Spine Surgery, The Second Hospital of Jilin University, Jilin University, Changchun, China.

出版信息

Front Bioeng Biotechnol. 2021 Dec 16;9:772853. doi: 10.3389/fbioe.2021.772853. eCollection 2021.

DOI:10.3389/fbioe.2021.772853
PMID:34976969
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8716838/
Abstract

Minimally invasive surgeries, including posterior endoscopic cervical foraminotomy (PECF), microsurgical anterior cervical foraminotomy (MACF), anterior transdiscal approach of endoscopic cervical discectomy (ATd-ECD), and anterior transcorporeal approach of endoscopic cervical discectomy (ATc-ECD), have obtained positive results for cervical spondylotic radiculopathy. Nonetheless, there is a lack of comparison among them regarding their biomechanical performance. The purpose of this study is to investigate the biomechanical changes of operated and adjacent segments after minimally invasive surgeries compared to a normal cervical spine. A three-dimensional model of normal cervical vertebrae C3-C7 was established using finite element analysis. Afterwards, four surgical models (PECF, MACF, ATd-ECD, and ATc-ECD) were constructed on the basis of the normal model. Identical load conditions were applied to simulate flexion, extension, lateral bending, and axial rotation of the cervical spine. We calculated the range of motion (ROM), intradiscal pressure (IDP), annulus fibrosus pressure (AFP), uncovertebral joints contact pressure (CPRESS), and facet joints CPRESS under different motions. For all circumstances, ATc-ECD was close to the normal cervical spine model, whereas ATd-ECD significantly increased ROM and joints CPRESS and decreased IDP in the operated segment. PECF increased more the operated segment ROM than did the MACF, but the MACF obtained maximum IDP and AFP. Except for ATc-ECD, the other models increased joints CPRESS of the operated segment. For adjacent segments, ROM, IDP, and joints CPRESS showed a downward trend in all models. All models showed good biomechanical stability. With their combination biomechanics, safety, and conditions of application, PECF and ATc-ECD could be appropriate choices for cervical spondylotic radiculopathy.

摘要

微创外科手术,包括后路内镜下颈椎椎间孔切开术(PECF)、显微外科前路颈椎椎间孔切开术(MACF)、内镜下颈椎间盘切除术的经椎间盘前路入路(ATd-ECD)以及内镜下颈椎间盘切除术的经椎体前路入路(ATc-ECD),在神经根型颈椎病的治疗中取得了积极成果。尽管如此,它们在生物力学性能方面缺乏相互比较。本研究的目的是探讨与正常颈椎相比,微创外科手术后手术节段及相邻节段的生物力学变化。利用有限元分析建立了正常颈椎C3-C7的三维模型。之后,在正常模型的基础上构建了四种手术模型(PECF、MACF、ATd-ECD和ATc-ECD)。施加相同的载荷条件以模拟颈椎的前屈、后伸、侧屈和轴向旋转。我们计算了不同运动状态下的活动范围(ROM)、椎间盘内压力(IDP)、纤维环压力(AFP)、钩椎关节接触压力(CPRESS)以及小关节CPRESS。在所有情况下,ATc-ECD与正常颈椎模型接近,而ATd-ECD显著增加了手术节段的ROM和关节CPRESS,并降低了手术节段的IDP。PECF比MACF更多地增加了手术节段的ROM,但MACF获得了最大的IDP和AFP。除ATc-ECD外,其他模型均增加了手术节段的关节CPRESS。对于相邻节段,所有模型中的ROM、IDP和关节CPRESS均呈下降趋势。所有模型均显示出良好的生物力学稳定性。综合其生物力学、安全性和应用条件,PECF和ATc-ECD可能是神经根型颈椎病的合适选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f902/8716838/458f42c14f3e/fbioe-09-772853-g007.jpg
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