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原发性侧索硬化症康复中机器人辅助步态训练的病例报告:一种新型康复方法的原理、可行性和潜在有效性

A Case Report on Robot-Aided Gait Training in Primary Lateral Sclerosis Rehabilitation: Rationale, Feasibility and Potential Effectiveness of a Novel Rehabilitation Approach.

作者信息

Portaro Simona, Ciatto Laura, Raciti Loredana, Aliberti Enrico, Aliberti Riccardo, Naro Antonino, Calabrò Rocco Salvatore

机构信息

All authors are with IRCCS Centro Neurolesi "Bonino-Pulejo" in Messina, Italy.

出版信息

Innov Clin Neurosci. 2021 Apr-Jun;18(4-6):15-19.

PMID:34980978
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8667707/
Abstract

Primary lateral sclerosis (PLS) is an adult-onset idiopathic disorder of the upper motor neuron system. Robot-aided rehabilitation with the Lokomat-Pro (LT) allows maximizing motor training by finely and individually controlling motor activation. No data are currently available on the use of robot-aided rehabilitation in PLS. The aim of this case study was to evaluate the effectiveness of a customized robotic rehabilitation protocol in PLS. A 54-year-old woman, diagnosed with PLS five years before admission, came to our clinic to undergo rehabilitation training due to gait difficulties with spastic paraparesis. The patient was treated with two different approaches: conventional physiotherapy followed by a combined approach (i.e. PT plus LT). After the conventional PT rehabilitation, no significant functional improvement was noted. However, the combined approach led to a significant improvement in functional motor skills, including walking, balance and lower limb muscle strength, and spasticity. Our experimental training combining robot-aided and conventional rehabilitation could be a promising approach to mitigate the PLS disability burden.

摘要

原发性侧索硬化症(PLS)是一种成人起病的上运动神经元系统特发性疾病。使用Lokomat-Pro(LT)进行机器人辅助康复能够通过精细且个性化地控制运动激活来最大化运动训练。目前尚无关于在PLS中使用机器人辅助康复的相关数据。本病例研究的目的是评估针对PLS的定制化机器人康复方案的有效性。一名54岁女性,入院前5年被诊断为PLS,因步态困难伴痉挛性截瘫前来我们诊所接受康复训练。该患者接受了两种不同的治疗方法:传统物理治疗,随后采用联合治疗方法(即物理治疗加LT)。经过传统的物理治疗康复后,未观察到明显的功能改善。然而,联合治疗方法使功能性运动技能得到了显著改善,包括步行、平衡和下肢肌肉力量,以及痉挛症状。我们将机器人辅助和传统康复相结合的实验性训练可能是减轻PLS残疾负担的一种有前景的方法。

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本文引用的文献

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Ann Clin Transl Neurol. 2019 Sep;6(9):1671-1680. doi: 10.1002/acn3.50864. Epub 2019 Aug 7.
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RETHINKING THE ROBOTIC REHABILITATION PATHWAY FOR PEOPLE WITH AMYOTROPHIC LATERAL SCLEROSIS: A NEED FOR CLINICAL TRIALS.重新思考肌萎缩侧索硬化症患者的机器人康复途径:临床试验的必要性。
Innov Clin Neurosci. 2019 Jan 1;16(1-2):11-12.
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Robotics for Lower Limb Rehabilitation.用于下肢康复的机器人技术
Phys Med Rehabil Clin N Am. 2019 May;30(2):385-397. doi: 10.1016/j.pmr.2018.12.012. Epub 2019 Mar 11.
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Motor Neuron Disease: Pathophysiology, Diagnosis, and Management.运动神经元病:病理生理学、诊断与管理。
Am J Med. 2019 Jan;132(1):32-37. doi: 10.1016/j.amjmed.2018.07.012. Epub 2018 Aug 1.
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A promising tool for flail arm in amyotrophic lateral sclerosis rehabilitation: a case report.有望成为肌萎缩侧索硬化症康复治疗中连枷臂的工具:病例报告。
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Advanced Robotic Therapy Integrated Centers (ARTIC): an international collaboration facilitating the application of rehabilitation technologies.高级机器人治疗集成中心(ARTIC):一个促进康复技术应用的国际合作。
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