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长期暴露于环境颗粒物与血压、高血压的关系:一项更新的系统评价和荟萃分析。

Association between long-term exposure to ambient particulate matter and blood pressure, hypertension: an updated systematic review and meta-analysis.

机构信息

Department of Urology, Xijing Hospital, the Fourth Military Medical University, Xi'an, China.

Department of Global Health, School of Health Sciences, Wuhan University, Wuhan, China.

出版信息

Int J Environ Health Res. 2023 Mar;33(3):268-283. doi: 10.1080/09603123.2021.2022106. Epub 2022 Jan 4.

DOI:10.1080/09603123.2021.2022106
PMID:34983264
Abstract

Evidence of more recent studies should be updated to evaluate the effect of long-term exposure to particulate matter (PM) on blood pressure and hypertension.        Studies of long-term effects of PM, PM and PM on blood pressure (SBP, DBP, MAP), hypertension were searched in Pubmed, Web of Science and Embase before May, 2021. Meta-analysis of 41 studies showed that exposure to PM, PM was associated with SBP (1.76 mmHg (95%CI:0.71, 2.80) and 0.63 mmHg (95%CI:0.40, 0.85), per 10 μg/m increase in PM), all three air pollutants (PM, PM, PM) was associated with DBP (1.16 mmHg (95%CI:0.34, 1.99), 0.31 mmHg (95%CI:0.16, 0.47), 1.17 mmHg (95%CI:0.24, 2.09), respectively. As for hypertension, PM, PM and PM were all significantly associated with higher risk of hypertension (OR=1.27 (95%CI:1.06, 1.52), 1.15 (95%CI:1.10, 1.20) and 1.11 (95%CI:1.07, 1.16). In conclusion, our study indicated a positive association between long-term exposure to particulate matter and increased blood pressure, hypertension.

摘要

有更多近期研究的证据应加以更新,以评估长期暴露于颗粒物(PM)对血压和高血压的影响。在 2021 年 5 月之前,我们在 Pubmed、Web of Science 和 Embase 中搜索了关于 PM、PM 和 PM 对血压(SBP、DBP、MAP)、高血压的长期影响的研究。荟萃分析 41 项研究表明,暴露于 PM、PM 与 SBP(每增加 10 μg/m,分别为 1.76 mmHg(95%CI:0.71,2.80)和 0.63 mmHg(95%CI:0.40,0.85))有关,所有三种空气污染物(PM、PM、PM)与 DBP(PM、PM、PM)有关(PM:1.16 mmHg(95%CI:0.34,1.99),0.31 mmHg(95%CI:0.16,0.47),1.17 mmHg(95%CI:0.24,2.09))。至于高血压,PM、PM 和 PM 均与高血压的风险增加显著相关(OR=1.27(95%CI:1.06,1.52),1.15(95%CI:1.10,1.20)和 1.11(95%CI:1.07,1.16))。总之,我们的研究表明,长期暴露于颗粒物与血压升高和高血压之间存在正相关关系。

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