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《世界卫生组织人类精液检查与处理实验室手册》第六版中的扩展精液检查：有助于理解男性生殖系统的功能。

Extended semen examinations in the sixth edition of the WHO Laboratory Manual for the Examination and Processing of Human Semen: contributing to the understanding of the function of the male reproductive system.

作者信息

Baldi Elisabetta, Gallagher Meurig T, Krasnyak Stepan, Kirkman-Brown Jackson

机构信息

Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.

Centre for Systems Modelling and Quantitative Biomedicine, University of Birmingham, Birmingham, United Kingdom; Centre for Human Reproductive Science, University of Birmingham, Birmingham, United Kingdom.

出版信息

Fertil Steril. 2022 Feb;117(2):252-257. doi: 10.1016/j.fertnstert.2021.11.034. Epub 2022 Jan 3.

DOI:10.1016/j.fertnstert.2021.11.034
PMID:34986981
Abstract

In the sixth edition of the World Health Organization manual for the examination and processing of human semen, extended examination methods to provide key diagnostics in the investigation of the male reproductive system function are elaborated. These go beyond the basic analysis of semen and may be useful in more specifically guiding the clinical characterization of fertile or infertile men. Among the extended examinations included in the chapter, the use of multiparametric scoring for sperm morphological defects, sperm DNA fragmentation, and the roles for computer-assisted analysis of sperm or semen are arguably those that will be the most widely used and may also cause the most debate.

摘要

在世界卫生组织人类精液检查与处理手册第六版中，阐述了扩展检查方法，以在男性生殖系统功能调查中提供关键诊断。这些方法超越了精液的基本分析，可能在更具体地指导生育或不育男性的临床特征方面有用。该章节中包含的扩展检查中，精子形态缺陷的多参数评分、精子DNA碎片化以及计算机辅助精子或精液分析的作用，可以说是将被最广泛使用的，也可能引发最多争议的方法。

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