Comprehensive Dental Care, The Nippon Dental University Niigata Hospital, Niigata, Japan.
Department of Oral and Maxillofacial Radiology, The Nippon Dental University School of Life Dentistry at Niigata, Niigata, Japan.
J Med Imaging Radiat Oncol. 2022 Oct;66(7):936-939. doi: 10.1111/1754-9485.13376. Epub 2022 Jan 5.
The quantitative parameter was successfully derived from the quantitative bone SPECT/CT images. The aim of this study was to evaluate maximum standardized uptake value (SUV) of normal structures in the head and neck with bone SPECT/CT.
Fifty-three patients with jaw lesions (11 chronic osteomyelitis, eight osteoradionecrosis and 34 medication-related osteonecrosis of the jaw) who had bone SPECT/CT were prospectively included. The maximum SUV of normal structures including vertebrae, sternal body, parietal bone and hyoid bone were analysed. Statistical analyses for the maximum SUV were performed by Pearson's rank correlation test. A P value lower than 0.05 was considered statistically significant.
The maximum SUVs of vertebrae, sternal body, parietal bone and hyoid bone of all patients were 8.10 ± 3.72, 5.16 ± 2.05, 3.67 ± 1.55 and 1.44 ± 0.56, respectively. Furthermore, the maximum SUV of vertebrae was significantly correlated with that of sternal body (Y = 0.527X + 5.388 (R = 0.084, P = 0.035)).
Maximum SUV with bone SPECT/CT should be useful for characterization of normal structures in the head and neck. Furthermore, the data reported herein can be used for reference in future studies and in clinical settings for head and neck lesions.
从定量骨 SPECT/CT 图像中成功获得了定量参数。本研究旨在评估骨 SPECT/CT 中头颈部正常结构的最大标准化摄取值（SUVmax）。
前瞻性纳入 53 例颌骨病变患者（11 例慢性骨髓炎、8 例放射性骨坏死和 34 例药物相关性颌骨坏死），行骨 SPECT/CT 检查。分析包括椎体、胸骨体、顶骨和舌骨在内的正常结构的 SUVmax。采用 Pearson 秩相关检验对 SUVmax 的最大值进行统计学分析。P 值小于 0.05 被认为具有统计学意义。
所有患者的椎体、胸骨体、顶骨和舌骨的 SUVmax 分别为 8.10±3.72、5.16±2.05、3.67±1.55 和 1.44±0.56。此外，椎体的 SUVmax 与胸骨体的 SUVmax 呈显著正相关（Y=0.527X+5.388（R=0.084，P=0.035））。
骨 SPECT/CT 的 SUVmax 对评估头颈部正常结构具有一定价值。此外，本研究报告的数据可作为未来研究和头颈部病变临床应用的参考。
