• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

单剂量奥硝唑治疗细菌性阴道病

Single dose of ornidazole in the treatment of bacterial vaginosis.

作者信息

Erkkola R, Järvinen H

机构信息

Department of Obstetrics and Gynecology, University Central Hospital, Turku, Finland.

出版信息

Ann Chir Gynaecol Suppl. 1987;202:94-6.

PMID:3499111
Abstract

Bacterial vaginosis is the most common cause of excessive and foul smelling vaginal discharge. In the group of 24 women, the diagnosis was based on increased vaginal discharge, positive KOH-test, and detection of clue cells in the wet smear. In the microbiological isolation, Gardnerella vaginalis was also observed in 20 subjects and mixed anaerobic flora in all the 24 subjects. A single dose of 1.5 g of ornidazole was given. Posttreatment control was performed 7 to 28 days later. Gardnerella vaginalis was present in 2 (cure rate 90%) and anaerobes in 4 subjects (cure rate 83%). Subjective improvement occurred in 96% of patients. Side effects, the most common of them being dizziness, after ornidazole treatment were observed by 17 (71%) of subjects.

摘要

细菌性阴道病是阴道分泌物过多且有异味的最常见原因。在24名女性组成的研究组中,诊断依据为阴道分泌物增多、KOH试验阳性以及在湿涂片检查中发现线索细胞。在微生物分离检查中,20名受试者检测出阴道加德纳菌,所有24名受试者均检测出混合厌氧菌。给予单剂量1.5克奥硝唑。7至28天后进行治疗后复查。2名受试者仍存在阴道加德纳菌(治愈率90%),4名受试者仍存在厌氧菌(治愈率83%)。96%的患者有主观症状改善。17名(71%)受试者在奥硝唑治疗后出现副作用,其中最常见的是头晕。

相似文献

1
Single dose of ornidazole in the treatment of bacterial vaginosis.单剂量奥硝唑治疗细菌性阴道病
Ann Chir Gynaecol Suppl. 1987;202:94-6.
2
Studies on the anaerobic (bacterial) vaginosis among the Bangladeshi women of reproductive age group.孟加拉国育龄妇女厌氧(细菌性)阴道病的研究。
Bangladesh Med Res Counc Bull. 1994 Dec;20(3):129-38.
3
Therapy of amine-vaginitis by a single dose of ornidazole (Tiberal); serum and tissue (vagina) concentrations of ornidazole after vaginal or rectal application.
Chemioterapia. 1987 Jun;6(2 Suppl):539-40.
4
Vaginal colonization with Gardnerella vaginalis and anaerobic curved rods.阴道加德纳菌和厌氧弯曲杆菌的阴道定植。
Scand J Urol Nephrol Suppl. 1984;86:147-52.
5
Gardnerella vaginalis and anaerobic bacteria in the etiology of bacterial (nonspecific) vaginosis.阴道加德纳菌和厌氧菌在细菌性(非特异性)阴道炎病因学中的作用
Scand J Infect Dis Suppl. 1983;40:41-6.
6
[Anaerobic bacteria and Gardnerella in nonspecific vaginal fluor (vaginosis)].
Gynakol Rundsch. 1984;24(1):1-23.
7
[Role of Gardnerella vaginalis and anaerobes. Etiology of nonspecific colpitis].
Fortschr Med. 1984 Mar 15;102(10):255-8.
8
Bacterial vaginosis.细菌性阴道病
West Indian Med J. 1989 Sep;38(3):126-32.
9
Microbiologic efficacy of intravaginal clindamycin cream for the treatment of bacterial vaginosis.阴道用克林霉素乳膏治疗细菌性阴道病的微生物学疗效
Obstet Gynecol. 1990 Sep;76(3 Pt 1):407-13.
10
[Use of ornidazole in the treatment of non-specific vaginitis caused by anaerobic bacteria. First experience].[奥硝唑用于治疗厌氧菌引起的非特异性阴道炎。初步经验]
Minerva Ginecol. 1987 Oct;39(10):715-7.

引用本文的文献

1
Screening for potent and selective anticlostridial leads among FDA-approved drugs.筛选 FDA 批准药物中的有效且选择性的抗梭菌先导化合物。
J Antibiot (Tokyo). 2020 Jun;73(6):392-409. doi: 10.1038/s41429-020-0288-3. Epub 2020 Mar 4.
2
A comparative study of oral single dose of metronidazole, tinidazole, secnidazole and ornidazole in bacterial vaginosis.口服单次剂量甲硝唑、替硝唑、塞克硝唑和奥硝唑治疗细菌性阴道病的比较研究。
Indian J Pharmacol. 2012 Mar;44(2):243-5. doi: 10.4103/0253-7613.93859.