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孟加拉国育龄妇女厌氧(细菌性)阴道病的研究。

Studies on the anaerobic (bacterial) vaginosis among the Bangladeshi women of reproductive age group.

作者信息

Naher A, Rahman K M, Hassan M M, Hoq J A

机构信息

Microbiology Deptt., Sir Salimullah Medical College, Dhaka.

出版信息

Bangladesh Med Res Counc Bull. 1994 Dec;20(3):129-38.

PMID:7748151
Abstract

Vaginal swab from 190 patients aged between 15 to 45 years with the complaint of excessive and foul smelling vaginal discharge and 50 healthy controls of comparable age were studied. Different diagnostic techniques used for the detection of G.vaginalis were compared. Antibiogram of isolated G.vaginalis was also performed to determine the drug sensitivity pattern. G. vaginalis were isolated from 74 patients (38.9%) and from 6 controls (12%). The rate of isolation of G. vaginalis in the vaginal swabs of patients is significantly higher (p < 0.001) as compared to controls. Vaginal flora in 91% of G. vaginalis positive patients were Gardnerella morphotype and clue cells were found in vaginal discharge in 85% of these cases. In contrast, vaginal flora of 92% control group were Lactobacilli morphotype N and no clue cell was detected. No pus cell was observed in the vaginal discharge of 66 (89.2%) of 74 patients infected with G. vaginalis. Amine test was positive in 81% G. vaginalis positive patients. The test was negative in all the control cases. Significance of these findings were discussed in detail.

摘要

对190例年龄在15至45岁之间、主诉阴道分泌物过多且有异味的患者以及50例年龄相仿的健康对照者进行了阴道拭子研究。比较了用于检测阴道加德纳菌的不同诊断技术。还对分离出的阴道加德纳菌进行了药敏试验,以确定药物敏感性模式。从74例患者(38.9%)和6例对照者(12%)中分离出阴道加德纳菌。与对照者相比,患者阴道拭子中阴道加德纳菌的分离率显著更高(p < 0.001)。91%阴道加德纳菌阳性患者的阴道菌群为加德纳菌形态型,其中85%的病例在阴道分泌物中发现线索细胞。相比之下,92%对照组的阴道菌群为乳酸杆菌形态型N,未检测到线索细胞。74例感染阴道加德纳菌的患者中,66例(89.2%)的阴道分泌物中未观察到脓细胞。81%阴道加德纳菌阳性患者的胺试验呈阳性。所有对照病例的该试验均为阴性。详细讨论了这些发现的意义。

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