Immune regulation in the tumor microenvironment and its relevance in cancer therapy.
作者信息
Zou Weiping
机构信息
Department of Surgery, Center of Excellence for Cancer Immunology and Immunotherapy, University of Michigan Rogel Cancer Center, Ann Arbor, MI, USA.
Department of Pathology, Graduate Program in Immunology and Graduate Program in Cancer Biology, University of Michigan School of Medicine, Ann Arbor, MI, USA.
出版信息
Cell Mol Immunol. 2022 Jan;19(1):1-2. doi: 10.1038/s41423-021-00738-0. Epub 2021 Dec 19.
Abstract
摘要
相似文献
1
Immune regulation in the tumor microenvironment and its relevance in cancer therapy.肿瘤微环境中的免疫调节及其在癌症治疗中的相关性。
Cell Mol Immunol. 2022 Jan;19(1):1-2. doi: 10.1038/s41423-021-00738-0. Epub 2021 Dec 19.
2
Advantages of targeting the tumor immune microenvironment over blocking immune checkpoint in cancer immunotherapy.在癌症免疫治疗中，靶向肿瘤免疫微环境优于阻断免疫检查点。
Signal Transduct Target Ther. 2021 Feb 20;6(1):72. doi: 10.1038/s41392-020-00449-4.
3
Editorial: The immunosuppressive tumor microenvironment and strategies to revert its immune regulatory milieu for cancer immunotherapy.社论：免疫抑制性肿瘤微环境以及逆转其免疫调节环境用于癌症免疫治疗的策略
Front Immunol. 2023 Jun 26;14:1238698. doi: 10.3389/fimmu.2023.1238698. eCollection 2023.
4
Reprogramming Tumor Microenvironment with Photothermal Therapy.光热疗法重编程肿瘤微环境。
Bioconjug Chem. 2020 May 20;31(5):1268-1278. doi: 10.1021/acs.bioconjchem.0c00135. Epub 2020 Apr 20.
5
Regulation of cancer-immunity cycle and tumor microenvironment by nanobiomaterials to enhance tumor immunotherapy.纳米生物材料调控肿瘤免疫循环和肿瘤微环境增强肿瘤免疫治疗
Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2020 Jul;12(4):e1612. doi: 10.1002/wnan.1612. Epub 2020 Mar 1.
6
Relevance of immune cell and tumor microenvironment imaging in the new era of immunotherapy.免疫细胞和肿瘤微环境成像在免疫治疗新时代的相关性。
J Exp Clin Cancer Res. 2020 May 18;39(1):89. doi: 10.1186/s13046-020-01586-y.
7
Suppressive Myeloid Cells Shape the Tumor Immune Microenvironment.抑制性髓系细胞塑造肿瘤免疫微环境。
Adv Biol (Weinh). 2021 Mar;5(3):e1900311. doi: 10.1002/adbi.201900311. Epub 2021 Feb 11.
8
Immunosuppressive Roles of Galectin-1 in the Tumor Microenvironment.半乳糖凝集素-1 在肿瘤微环境中的免疫抑制作用。
Biomolecules. 2021 Sep 23;11(10):1398. doi: 10.3390/biom11101398.
9
TLR-mediated metabolic reprogramming in the tumor microenvironment: potential novel strategies for cancer immunotherapy.TLR 介导的肿瘤微环境代谢重编程：癌症免疫治疗的潜在新策略。
Cell Mol Immunol. 2018 May;15(5):428-437. doi: 10.1038/cmi.2018.4. Epub 2018 Mar 19.
10
Local targets for immune therapy to cancer: tumor draining lymph nodes and tumor microenvironment.癌症免疫治疗的局部靶点：肿瘤引流淋巴结和肿瘤微环境。
Int J Cancer. 2013 May 1;132(9):1971-6. doi: 10.1002/ijc.27755. Epub 2012 Aug 16.
引用本文的文献
1
PANoptosis in cancer: bridging molecular mechanisms to therapeutic innovations.癌症中的全程序死亡：将分子机制与治疗创新相联系
Cell Mol Immunol. 2025 Jul 28. doi: 10.1038/s41423-025-01329-z.
2
Integrative bioinformatics analysis identifies METTL1 as a regulator of immune infiltration and prognosis in breast cancer.整合生物信息学分析确定METTL1为乳腺癌免疫浸润和预后的调节因子。
Sci Rep. 2025 Jul 19;15(1):26297. doi: 10.1038/s41598-025-11391-2.
3
Battlegrounds of treatment resistance: decoding the tumor microenvironment.治疗耐药的战场：解读肿瘤微环境
Naunyn Schmiedebergs Arch Pharmacol. 2025 Mar 25. doi: 10.1007/s00210-025-04055-5.
4
Application of tumor organoids simulating the tumor microenvironment in basic and clinical research of tumor immunotherapy.模拟肿瘤微环境的肿瘤类器官在肿瘤免疫治疗基础与临床研究中的应用
Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2024 Aug 28;49(8):1316-1326. doi: 10.11817/j.issn.1672-7347.2024.240187.
5
Identification and Verification of a Novel Disulfidptosis-Related lncRNAs Prognostic Signature to Predict the Prognosis and Immune Activity of Head and Neck Squamous Carcinoma.一种用于预测头颈部鳞状细胞癌预后和免疫活性的新型二硫化物依赖性细胞程序性坏死相关长链非编码RNA预后特征的鉴定与验证
Iran J Public Health. 2024 Oct;53(10):2328-2340. doi: 10.18502/ijph.v53i10.16720.
6
NIR laser-activated phthalocyanine loaded lipid nanoparticles targeting M2 macrophage for improved photoacoustic imaging-guided photothermal therapy.靶向M2巨噬细胞的近红外激光激活酞菁负载脂质纳米颗粒用于改善光声成像引导的光热治疗
Mater Today Bio. 2024 Aug 24;28:101209. doi: 10.1016/j.mtbio.2024.101209. eCollection 2024 Oct.
7
Neutrophil-like Monocytes Increase in Patients with Colon Cancer and Induce Dysfunctional TIGIT+ NK Cells.中性粒细胞样单核细胞在结肠癌患者中增加，并诱导功能失调的 TIGIT+NK 细胞。
Int J Mol Sci. 2024 Aug 2;25(15):8470. doi: 10.3390/ijms25158470.
8
Aerobic glycolysis enables the effector differentiation potential of stem-like CD4 T cells to combat cancer.有氧糖酵解赋予了干细胞样CD4 T细胞对抗癌症的效应细胞分化潜能。
Cell Mol Immunol. 2024 May;21(5):527-529. doi: 10.1038/s41423-024-01154-w. Epub 2024 Mar 21.
9
Tumor-derived extracellular vesicle drug delivery system for chemo-photothermal-immune combination cancer treatment.用于化疗-光热-免疫联合癌症治疗的肿瘤源性细胞外囊泡给药系统
iScience. 2024 Jan 8;27(2):108833. doi: 10.1016/j.isci.2024.108833. eCollection 2024 Feb 16.
10
MiRNA signatures in nasopharyngeal carcinoma: molecular mechanisms and therapeutic perspectives.鼻咽癌中的微小RNA特征：分子机制与治疗前景
Am J Cancer Res. 2023 Dec 15;13(12):5805-5824. eCollection 2023.
本文引用的文献
1
PD-L1 expression by dendritic cells is a key regulator of T-cell immunity in cancer.树突状细胞的程序性死亡配体1（PD-L1）表达是癌症中T细胞免疫的关键调节因子。
Nat Cancer. 2020 Jul;1(7):681-691. doi: 10.1038/s43018-020-0075-x. Epub 2020 Jun 22.
2
Dendritic cells in cancer immunology.癌症免疫学中的树突状细胞。
Cell Mol Immunol. 2022 Jan;19(1):3-13. doi: 10.1038/s41423-021-00741-5. Epub 2021 Sep 3.
3
Regulation of antitumor immunity by inflammation-induced epigenetic alterations.炎症诱导的表观遗传改变对肿瘤免疫的调控。
Cell Mol Immunol. 2022 Jan;19(1):59-66. doi: 10.1038/s41423-021-00756-y. Epub 2021 Aug 31.
4
Tissue-specific Tregs in cancer metastasis: opportunities for precision immunotherapy.癌症转移中的组织特异性 Tregs：精准免疫治疗的机遇。
Cell Mol Immunol. 2022 Jan;19(1):33-45. doi: 10.1038/s41423-021-00742-4. Epub 2021 Aug 20.
5
IFNγ signaling integrity in colorectal cancer immunity and immunotherapy.IFNγ 信号在结直肠癌免疫和免疫治疗中的完整性。
Cell Mol Immunol. 2022 Jan;19(1):23-32. doi: 10.1038/s41423-021-00735-3. Epub 2021 Aug 12.
6
CD40 stimulation as a molecular adjuvant for cancer vaccines and other immunotherapies.CD40 刺激作为癌症疫苗和其他免疫疗法的分子佐剂。
Cell Mol Immunol. 2022 Jan;19(1):14-22. doi: 10.1038/s41423-021-00734-4. Epub 2021 Jul 19.
7
The therapeutic implications of immunosuppressive tumor aerobic glycolysis.免疫抑制性肿瘤有氧糖酵解的治疗意义。
Cell Mol Immunol. 2022 Jan;19(1):46-58. doi: 10.1038/s41423-021-00727-3. Epub 2021 Jul 8.
8
Host expression of PD-L1 determines efficacy of PD-L1 pathway blockade-mediated tumor regression.宿主表达 PD-L1 决定 PD-L1 通路阻断介导的肿瘤消退疗效。
J Clin Invest. 2018 Feb 1;128(2):805-815. doi: 10.1172/JCI96113. Epub 2018 Jan 16.
9
PD-L1 on host cells is essential for PD-L1 blockade-mediated tumor regression.宿主细胞上的 PD-L1 对于 PD-L1 阻断介导的肿瘤消退是必需的。
J Clin Invest. 2018 Feb 1;128(2):580-588. doi: 10.1172/JCI96061. Epub 2018 Jan 16.
10
Immunosuppressive networks in the tumour environment and their therapeutic relevance.肿瘤环境中的免疫抑制网络及其治疗意义。
Nat Rev Cancer. 2005 Apr;5(4):263-74. doi: 10.1038/nrc1586.
Zotero 插件