Bajwa Mohammad Hamza, Ul Islam Mohammad Yousuf, Mubarak Fatima
Department of Neurosurgery, Aga Khan University Hospital, Aga Khan University, Karachi, Sindh, Pakistan.
Department of Radiology, Aga Khan University Hospital, Aga Khan University, Karachi, Sindh, Pakistan.
Surg Neurol Int. 2021 Dec 14;12:613. doi: 10.25259/SNI_990_2021. eCollection 2021.
Giant tumefactive perivascular spaces (TPVS) are radiological rarities and may mimic other neurological structural lesions. Fewer than 80 cases have been reported in the literature with even fewer in the pediatric population.
The authors present an image report showcasing a 3-year-old boy presenting with uncontrolled seizures despite multiple anti-epileptic medications. His magnetic resonance imaging showed multiple, non-contrast enhancing cyst clusters within the left parieto-occipital region that was hyperintense on T2-weighted imaging, and isointense to cerebrospinal fluid. Due to a characteristic absence of perilesional edema seen on fluid-attenuated inversion recovery imaging or diffusion restriction on diffusion-weighted imaging (DWI) sequences, this was diagnosed as a giant TPVS.
Accurate diagnosis of these rare radiological entities is based on pathognomonic findings that can help prevent unnecessary surgery and guide management for patients, particularly in the pediatric population as seen in our case.
巨大型瘤样血管周围间隙(TPVS)在影像学上较为罕见,可能会模仿其他神经结构病变。文献报道的病例少于80例,儿科患者更是少之又少。
作者展示了一份影像报告,该报告描述了一名3岁男孩,尽管使用了多种抗癫痫药物,但癫痫发作仍无法得到控制。他的磁共振成像显示左顶枕区有多个无强化的囊肿簇,在T2加权成像上呈高信号,与脑脊液等信号。由于在液体衰减反转恢复成像上未发现典型的病灶周围水肿,在扩散加权成像(DWI)序列上也无扩散受限,因此诊断为巨大型TPVS。
准确诊断这些罕见的影像学实体基于具有诊断意义的表现,这有助于避免不必要的手术,并指导患者的治疗,尤其是像我们病例中的儿科患者。