Abna Zohreh, Fazeli Seyed Amirhossein, Mirhashemi Seyedhadi, Mirzaei Khadijeh, Emami Farbod, Jamili Shahin, Dehghani Reza
MS Fellowship, Department of Neurology, Tehran University of Medical Sciences, Tehran, Iran.
Nephrologist, Department of Internal Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Ann Indian Acad Neurol. 2021 Sep-Oct;24(5):664-667. doi: 10.4103/aian.AIAN_235_21. Epub 2021 Oct 14.
Obesity is a major public health concern and should be considered in autoimmune inflammatory disorders, such as multiple sclerosis (MS). In these patients, obesity leads to increasing comorbidities as well as reduced quality of life. Obesity causes an inflammatory state in the body, especially in adolescents; obesity has a role in the pathogenesis of MS. Hence, it is identified as a lifestyle modifiable risk factor for MS disease. Among various treatments for obesity, bariatric surgery has been widely used. Although few studies have been performed on bariatric surgery in MS patients, in this review, we present the existing data regarding the effects of obesity on the MS course and evaluate the outcomes of bariatric surgery among this population.
肥胖是一个主要的公共卫生问题，在自身免疫性炎症性疾病，如多发性硬化症（MS）中应予以考虑。在这些患者中，肥胖会导致合并症增加以及生活质量下降。肥胖会在体内引发炎症状态，尤其是在青少年中；肥胖在MS的发病机制中起作用。因此，它被确定为MS疾病的一种可通过生活方式改变的风险因素。在各种肥胖治疗方法中，减肥手术已被广泛应用。尽管针对MS患者进行减肥手术的研究很少，但在本综述中，我们展示了关于肥胖对MS病程影响的现有数据，并评估了该人群中减肥手术的效果。
