Hamamura Toshitaka, Suganuma Shinichiro, Takano Ayumi, Matsumoto Toshihiko, Shimoyama Haruhiko
National Center for Cognitive Behavior Therapy and Research, National Center of Neurology and Psychiatry, Tokyo, Japan.
Japan Society for the Promotion of Science, Tokyo, Japan.
Addict Behav Rep. 2021 Dec 14;15:100400. doi: 10.1016/j.abrep.2021.100400. eCollection 2022 Jun.
This study aimed (1) to delineate how a web-based intervention affects the problem drinking behaviors of Japanese adults and (2) to examine the moderating effects of disorder levels and alcohol outcome expectancies on intervention outcomes.
We implemented an online two-armed parallel-group randomized controlled trial with 546 Japanese adults. Adults aged 20 years or older and who scored eight or higher on the Alcohol Use Disorder Identification Test were included in this study. Participants were randomly allocated to the intervention group or the waitlist/control group. The intervention comprised assessment of drinking behavior, personalized normative feedback, psychoeducation about the consequences of problem drinking, and a short quiz. The outcomes were weekly drinking quantity and abstinent days, largest drinking quantity in one day, and alcohol-related consequences reported at baseline and at one-, two-, and six-month follow-ups. A mixed-effects model regression was conducted to compare the intervention and control groups.
The attrition rates at each follow-up were 52.93%, 49.45%, and 32.60%, respectively. The time × condition interaction effect on weekly drinking quantity was significant at the two- and six-month follow-ups, = 0.28, 95% CI [0.04, 0.51], = 0.34, 95% CI [0.05, 0.63], respectively. Moderations related to the intervention effect were not statistically significant.
A web-based intervention was found to be effective for two and six months only on drinking quantity measures of Japanese adults with problem drinking. Limitations including high drop-out rates in are discussed.
本研究旨在（1）描述基于网络的干预如何影响日本成年人的问题饮酒行为，以及（2）检验障碍水平和酒精结果预期对干预效果的调节作用。
我们对546名日本成年人进行了一项在线双臂平行组随机对照试验。本研究纳入了年龄在20岁及以上且酒精使用障碍识别测试得分在8分或以上的成年人。参与者被随机分配到干预组或等待列表/对照组。干预包括饮酒行为评估个性化规范反馈、关于问题饮酒后果的心理教育以及一个简短测验。结果指标为基线时以及1个月、2个月和6个月随访时报告的每周饮酒量、戒酒天数、一天内最大饮酒量以及与酒精相关的后果。采用混合效应模型回归比较干预组和对照组。
每次随访时的失访率分别为52.93%、49.45%和32.60%。在2个月和6个月随访时，时间×条件交互作用对每周饮酒量的影响显著，分别为 = 0.28，95%置信区间[0.04, 0.51]， = 0.34，95%置信区间[0.05, 0.63]。与干预效果相关的调节作用无统计学意义。
发现基于网络的干预仅在2个月和6个月内对有问题饮酒的日本成年人的饮酒量指标有效。讨论了包括高失访率在内的局限性。
