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乌兹别克斯坦共和国肝脏及其他器官棘球蚴病的流行病学特征

Epidemiological aspects of echinococcosis of the liver and other organs in the Republic of Uzbekistan.

作者信息

Babadjanov Azam Khasanovich, Yakubov Farkhod Radjabovich, Ruzmatov Palvannazir Yuldashevich, Sapaev Duschan Shukhratovich

机构信息

Department of Surgery of Portal Hypertension, Pancreatoduodenal Zone and Liver Transplantation of the Republican Specialized Scientific and Practical Medical Center of Surgery named after Academician V.Vakhidov, Tashkent, Uzbekistan.

Department of Surgery of Abdominal of the Khorezm Regional Multidisciplinary Medical Center, Urgench, Uzbekistan.

出版信息

Parasite Epidemiol Control. 2021 Nov 24;15:e00230. doi: 10.1016/j.parepi.2021.e00230. eCollection 2021 Nov.

DOI:10.1016/j.parepi.2021.e00230
PMID:35005264
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8716672/
Abstract

INTRODUCTION

Recently, in international medical organizations, more and more interest is shown towards diseases in humans, among which the cystic form of echinococcosis (CE) is given special importance. As a zoonotic parasitic disease caused by the larval stage of cestodes belonging to the genus Echinococcus and the Taeniidae family, CE in 2014 was recognized globally by the UN Food and Agriculture Organization (FAO) and WHO as the second most important foodborne parasitic pathology. In the 2018, the European Food Safety Authority (EFSA) considered CE among the food-borne parasites of highest relevance in Europe.

PURPOSE

to study the actual epidemiology of human echinococcosis lesion in the Republic of Uzbekistan for 2015-2019 to highlight the mean annual incidence of this pathology in all regions of the country, as well as the extensive value of the proportion of echinococcosis of the liver (EL), lungs (LE) and other localizations.

MATERIAL AND METHODS

The officially registered data for all regions of the country for 2015-2019 were studied. An ultrasound screening of the abdominal organs of the population of the Khorezm region was carried out during 2019 to determine the effectiveness of early diagnosis of EL. A total of 104,284 inhabitants were examined, of which 38,660 were children and 65,624 were adults.

RESULTS

According to the processed statistical data for all regions of the Republic of Uzbekistan for 2015-2019 on average, 2105.0 ± 43.3 patients with echinococcosis of various localizations were diagnosed. The mean annual incidence was 6.5 ± 0.09 per 100,000 inhabitants. The extensive value of the EL share was 79.4 ± 0.9% (1672.2 ± 35.6 on average per year), high-level rate - 5.2 ± 0.08 per 100,000 inhabitants; the proportion of LE was 14.0 ± 0.8% (295.2 ± 17.8), the prevalence was 0.9 ± 0.06 per 100,000 inhabitants; the proportion of echinococcosis of other localizations was 6.5 ± 0.5% (137.6 ± 13.4), the high-level value was 0.4 ± 0.03 per 100,000 inhabitants. The frequency of detection of the liver or other abdominal organs echinococcosis during screening ultrasound in the Khorezm region was 0.009%, in turn, the examination of family members of these patients increased this indicator to 0.011%.

摘要

引言

最近,在国际医学组织中,人们对人类疾病的关注度越来越高,其中囊性棘球蚴病(CE)受到特别重视。作为一种由棘球绦虫属幼虫阶段引起的人畜共患寄生虫病,属于带科,2014年CE被联合国粮食及农业组织(FAO)和世界卫生组织(WHO)全球确认为第二重要的食源性寄生虫病。2018年,欧洲食品安全局(EFSA)将CE列为欧洲最相关的食源性寄生虫之一。

目的

研究2015 - 2019年乌兹别克斯坦共和国人类棘球蚴病病变的实际流行病学,以突出该国所有地区这种疾病的年平均发病率,以及肝棘球蚴病(EL)、肺棘球蚴病(LE)和其他部位棘球蚴病所占比例的广泛数值。

材料与方法

研究了该国2015 - 2019年所有地区的官方登记数据。2019年对花拉子模地区居民的腹部器官进行了超声筛查,以确定EL早期诊断的有效性。共检查了104284名居民,其中儿童38660名,成人65624名。

结果

根据对乌兹别克斯坦共和国2015 - 2019年所有地区处理后的统计数据,平均诊断出2105.0±43.3例不同部位的棘球蚴病患者。年平均发病率为每10万居民6.5±0.09例。EL所占比例的广泛数值为79.4±0.9%(平均每年1672.2±35.6例),高水平发病率为每10万居民5.2±0.08例;LE所占比例为14.0±0.8%(295.2±17.8例),患病率为每10万居民0.9±0.06例;其他部位棘球蚴病所占比例为6.5±0.5%(137.6±13.4例),高水平数值为每1十万居民0.4±0.03例。在花拉子模地区筛查超声检查期间,肝脏或其他腹部器官棘球蚴病的检出频率为万分之0.009,而对这些患者家庭成员的检查使该指标提高到万分之0.011。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba31/8716672/7ce22253d54a/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba31/8716672/7ce22253d54a/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba31/8716672/7ce22253d54a/gr1.jpg

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