国家癌症研究所指定癌症中心的传播和实施研究及培训补助金的流行情况。

The Prevalence of Dissemination and Implementation Research and Training Grants at National Cancer Institute-Designated Cancer Centers.

机构信息

Department of Social and Behavioral Sciences, Harvard T.H. Chan School of Public Health, Boston, MA, USA.

Dana-Farber/Harvard Cancer Center, Boston, MA, USA.

出版信息

JNCI Cancer Spectr. 2021 Dec 15;6(1). doi: 10.1093/jncics/pkab092. eCollection 2022 Feb.

Abstract

BACKGROUND

Dissemination and implementation (D&I) research is a key factor in the uptake and use of evidence-based cancer control interventions. National Cancer Institute (NCI)-designated cancer centers are ideal settings in which to further D&I knowledge. The purpose of this study was to summarize the characteristics of NCI-funded D&I science grants in the nation's cancer centers to understand the nature, extent, and opportunity for this key type of translational work.

METHODS

We used the National Institutes of Health Research Portfolio Online Reporting Tool to identify active NCI-funded grants in D&I science at NCI clinical cancer centers (n = 13) and comprehensive cancer centers (n = 51) as well as their academic affiliates. Active projects were eligible for inclusion if they 1) were awarded directly to an NCI cancer center or an academic or research affiliate, and 2) identified D&I content in the abstract. Portfolio data were collected in February 2021.

RESULTS

We identified 104 active NCI-funded D&I research or training grants across the 64 cancer centers; 57.8% of cancer centers had at least 1 NCI-funded D&I grant. Most awards (71.1%) were for research grants. Training grants constituted 29.1% of D&I-focused grants. Overall, 50.0% of grants (n = 52) concentrated on specific cancers. Almost two-thirds of grants (n = 68, 65.4%) had a stated health equity focus.

CONCLUSIONS

More than one-half of NCI-designated cancer centers have active funding in D&I science, reflecting a substantial investment by NCI. There remains considerable room for further development, which would further support NCI's translational mission.

摘要

背景

传播和实施(D&I)研究是采用基于证据的癌症控制干预措施的关键因素。美国国立卫生研究院(NCI)指定的癌症中心是进一步开展 D&I 知识的理想场所。本研究的目的是总结美国国家癌症中心 NCI 资助的 D&I 科学研究的特点,以了解这种关键类型的转化工作的性质、程度和机会。

方法

我们使用美国国立卫生研究院研究组合在线报告工具,确定 NCI 临床癌症中心(n=13)和综合癌症中心(n=51)及其学术附属机构中 NCI 资助的 D&I 科学领域的活跃项目。如果符合以下条件,活跃项目有资格入选:1)直接授予 NCI 癌症中心或学术或研究附属机构,2)摘要中确定了 D&I 内容。项目组合数据于 2021 年 2 月收集。

结果

我们在 64 个癌症中心中确定了 104 项 NCI 资助的 D&I 研究或培训项目;57.8%的癌症中心至少有 1 项 NCI 资助的 D&I 项目。大多数奖项(71.1%)是研究赠款。培训赠款占 D&I 重点赠款的 29.1%。总体而言,50.0%(n=52)的赠款集中于特定癌症。近三分之二的赠款(n=68,65.4%)明确关注健康公平问题。

结论

超过一半的 NCI 指定癌症中心在 D&I 科学领域有活跃的资金,这反映了 NCI 的大量投资。还有相当大的发展空间,这将进一步支持 NCI 的转化任务。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c23/8735751/6b6162cca41c/pkab092f1.jpg

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