Department of Applied Chemistry, Graduate School of Engineering, Osaka University, Suita, Osaka 565-0871, Japan.
Innovative Catalysis Science Division, Institute for Open and Transdisciplinary Research Initiatives (ICS-OTRI), Osaka University, Suita, Osaka 565-0871, Japan.
J Am Chem Soc. 2022 Jan 19;144(2):662-666. doi: 10.1021/jacs.1c09265. Epub 2022 Jan 10.
C(aryl)-C(═O) bonds of aryl amides can be activated and added across alkenes with the aid of a nickel catalyst. This 1,2-carboaminocarbonylation reaction enables the dicarbofunctionalization of alkenes with an atom economy of 100%.
芳基酰胺的 C(aryl)-C(═O)键可以在镍催化剂的帮助下被激活并与烯烃加成。这种 1,2-碳氮键羰基化反应可以实现烯烃的双官能团化，原子经济性为 100%。
