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青年大学生的食物消费与代谢风险。

Food Consumption and Metabolic Risks in Young University Students.

机构信息

Division de Ciencias Biomedicas, Centro Universitario de los Altos, Universidad de Guadalajara, Rafael Casillas Aceves 1200, Tepatitlan de Morelos 47620, Mexico.

Division de Ciencias Agropecuarias e Ingenierias, Centro Universitario de los Altos, Universidad de Guadalajara, Rafael Casillas Aceves 1200, Tepatitlan de Morelos 47620, Mexico.

出版信息

Int J Environ Res Public Health. 2021 Dec 31;19(1):449. doi: 10.3390/ijerph19010449.

Abstract

The purpose of this study was to analyze the association between components of the diet, metabolic risks, and the serum concentrations of adiponectin and interleukin-6 (IL-6). With prior informed consent, an analytical cross-sectional study was carried out with 72 students in their first year of university. The subjects had a mean age of 19.2 ± 1.0 years and body mass index of 23.38 ± 4.2, and they were mainly women (80.6%). Sociodemographic, anthropometric, and dietary data and metabolic risk factors were evaluated, and biochemical parameters and adipocytokines were also considered. The data were analyzed using means, ranges, and correlations, as well as principal components. In general, the protein, fat, and sodium intake were higher than the international dietary recommendations, and deficiencies in vitamins B5 and E, potassium, phosphorus, selenium, and zinc were observed. The most frequently observed metabolic risks were insulin resistance and hypoalphalipoproteinemia. IL-6 was positively correlated with lipid and protein intake. Adiponectin showed a positive correlation with high-density lipoprotein and a negative correlation with insulin, weight, and waist, while the adiponectin pattern was similar to that of vitamins E and A, which decreased with increasing intake of calories, macronutrients, and sodium. In general, a hypercaloric diet that was high in protein, fat, and sodium and deficient in vitamins, mainly fat-soluble, was associated with a lower concentration of adiponectin and a higher concentration of IL-6, which favor the presence of metabolic risks, including insulin resistance. Intervention studies are required to evaluate the dietary intake of metabolic markers in young people without comorbidities, which will lay the foundation for implementing prevention strategies.

摘要

本研究旨在分析饮食成分、代谢风险与脂联素和白细胞介素-6(IL-6)血清浓度之间的关联。在获得事先知情同意后,我们对 72 名大学一年级学生进行了一项分析性横断面研究。研究对象的平均年龄为 19.2 ± 1.0 岁,体重指数为 23.38 ± 4.2,且主要为女性(80.6%)。评估了社会人口统计学、人体测量学和饮食数据以及代谢风险因素,并考虑了生化参数和脂肪细胞因子。使用平均值、范围和相关性以及主成分分析对数据进行分析。总的来说,蛋白质、脂肪和钠的摄入量高于国际饮食建议,并且观察到维生素 B5 和 E、钾、磷、硒和锌的缺乏。最常见的代谢风险是胰岛素抵抗和低高密度脂蛋白血症。IL-6 与脂质和蛋白质摄入呈正相关。脂联素与高密度脂蛋白呈正相关,与胰岛素、体重和腰围呈负相关,而脂联素模式与维生素 E 和 A 相似,随着卡路里、宏量营养素和钠摄入的增加而降低。总的来说,高蛋白、高脂肪和高钠的高卡路里饮食,以及维生素缺乏症,主要是脂溶性维生素缺乏症,与脂联素浓度降低和白细胞介素-6 浓度升高相关,这有利于代谢风险的出现,包括胰岛素抵抗。需要进行干预研究来评估无合并症的年轻人的代谢标志物的饮食摄入,这将为实施预防策略奠定基础。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/526a/8744619/35538ec8a869/ijerph-19-00449-g001.jpg

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