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亚洲大黄蜂,1836 年 Lepeletier(膜翅目:胡蜂科),基于电刺激方案的毒液获取。

Asian Hornet, Lepeletier 1836 (Hym.: Vespidae), Venom Obtention Based on an Electric Stimulation Protocol.

机构信息

Academy of Veterinary Sciences of Galicia, Edificio EGAP, Rúa Madrid, No. 2-4, 15707 Santiago de Compostela, (A Coruña), Spain.

Fundación Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Hospital Clínico, Edificio D, 1ª Planta, Travesía da Choupana S/N, 15706 Santiago de Compostela, (A Coruña), Spain.

出版信息

Molecules. 2021 Dec 27;27(1):138. doi: 10.3390/molecules27010138.

DOI:10.3390/molecules27010138
PMID:35011370
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8746500/
Abstract

The yellow-legged Asian hornet ( Lepeletier 1836 (Hymenoptera: Vespidae)) is naturally distributed in China, Southeast Asia, and India; however, recently it has been detected outside of its native area, confirmed as being established in South Korea, Europe, and Japan. Health risks and deaths caused by the invasive stings have become a public health concern, being the most common cause of anaphylaxis due to hymenopterans in some European regions. This in turn has led to increased demand from medical practitioners and researchers for venom for diagnostic and therapeutic purposes. In this study, a straightforward, quick, and inexpensive method for obtaining venom by electric stimulation is described. The venom extracts were analyzed by nuclear magnetic resonance spectroscopy (H-NMR). The availability of venom will lead to improved diagnostic and therapeutic methods, mainly by venom immunotherapy (VIT), in patients allergic to this invasive species.

摘要

黄脚胡蜂(Lepeletier 1836(膜翅目:胡蜂科))自然分布于中国、东南亚和印度;然而,最近在其原生区域以外的地方也发现了它,在韩国、欧洲和日本已经确定它已经建立了种群。入侵性的蛰刺所造成的健康风险和死亡已经成为公共卫生关注的问题,在一些欧洲地区,它是膜翅目昆虫引起过敏反应的最常见原因。这反过来又导致医疗从业者和研究人员对毒液的需求增加,以用于诊断和治疗目的。在这项研究中,描述了一种通过电刺激获得毒液的简单、快速且廉价的方法。毒液提取物通过核磁共振波谱(H-NMR)进行分析。毒液的可用性将导致对这种入侵物种过敏的患者的诊断和治疗方法得到改善,主要是通过毒液免疫疗法(VIT)。

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