Graduate School of Life and Environmental Sciences, Kyoto Prefectural University, Kyoto 606-8522, Japan.
Nutrients. 2020 Oct 19;12(10):3189. doi: 10.3390/nu12103189.
Skeletal muscle, the largest organ in the human body, accounting for approximately 40% of body weight, plays important roles in exercise and energy expenditure. In the elderly, there is often a progressive decline in skeletal muscle mass and function, a condition known as sarcopenia, which can lead to bedridden conditions, wheelchair confinement as well as reducing the quality of life (QOL). In developed countries with aging populations, the prevention and management of sarcopenia are important for the improvement of health and life expectancy in these populations. Recently, vitamin D, a fat-soluble vitamin, has been attracting attention due to its importance in sarcopenia. This review will focus on the effects of vitamin D deficiency and supplementation on sarcopenia.
骨骼肌是人体最大的器官，占体重的约 40%，在运动和能量消耗中发挥着重要作用。在老年人中，骨骼肌质量和功能常常逐渐下降，这种情况被称为肌肉减少症，可导致卧床不起、轮椅受限以及降低生活质量。在人口老龄化的发达国家，预防和管理肌肉减少症对于提高这些人群的健康和预期寿命非常重要。最近，脂溶性维生素维生素 D 因其在肌肉减少症中的重要性而受到关注。本综述将重点讨论维生素 D 缺乏和补充对肌肉减少症的影响。
