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“无化合物麻醉”、精准给药与术后恢复加速:关于理论纳米医学应用的思考

"Compoundless Anaesthesia", Controlled Administration, and Post-Operative Recovery Acceleration: Musings on Theoretical Nanomedicine Applications.

作者信息

Jaynes Tyler Lance

机构信息

Alden March Bioethics Institute, Albany Medical College, Albany, NY 12208, USA.

Society for HealthCare Innovation (SHCI), Philadelphia, PA 19146, USA.

出版信息

J Clin Med. 2022 Jan 4;11(1):256. doi: 10.3390/jcm11010256.

Abstract

Much research has been conducted on how patients may be served through new advances in perioperative anaesthetic care. However, adaptations of standardised care methodologies can only provide so many novel solutions for patients and caregivers alike. Similarly, unique methods such as nanoscopic liposomal package delivery for analgesics and affective numbing agents pose a similar issue-specifically that we are still left with the dilemma of patients for whom analgesics and numbing agents are ineffective or harmful. An examination of the potential gains that may result from the targeted development of nanorobotics for anaesthesia in perioperative care will be presented in this essay to help resolve this pending conflict for the research community. This examination should therefore serve as a "call to action" for such research and a "primer" for those for whom the method's implementation would most directly impact.

摘要

关于如何通过围手术期麻醉护理的新进展为患者提供服务,已经进行了大量研究。然而,标准化护理方法的调整只能为患者和护理人员提供有限的新解决方案。同样,诸如纳米级脂质体包裹递送镇痛药和情感麻木剂等独特方法也存在类似问题,具体而言,对于那些镇痛药和麻木剂无效或有害的患者,我们仍然面临困境。本文将探讨围手术期护理中针对麻醉的纳米机器人靶向开发可能带来的潜在收益,以帮助研究界解决这一悬而未决的冲突。因此,这项研究应成为此类研究的“行动呼吁”,并为那些该方法的实施将产生最直接影响的人提供“入门指南”。

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