Health Sciences North Research Institute, 56 Walford Rd, Sudbury, ON, P3E 2H2, Canada.
Flosonics Medical, 325 Front Street, Toronto, ON, M5V 2Y1, Canada.
BMC Res Notes. 2022 Jan 10;15(1):7. doi: 10.1186/s13104-021-05896-y.
Doppler ultrasonography of the common carotid artery is used to infer stroke volume change and a wearable Doppler ultrasound has been designed to improve this workflow. Previously, in a human model of hemorrhage and resuscitation comprising approximately 50,000 cardiac cycles, we found a strong, linear correlation between changing stroke volume, and measures from the carotid Doppler signal, however, optimal Doppler thresholds for detecting a 10% stroke volume change were not reported. In this Research Note, we present these thresholds, their sensitivities, specificities and areas under their receiver operator curves (AUROC).
Augmentation of carotid artery maximum velocity time integral and corrected flowtime by 18% and 4%, respectively, accurately captured 10% stroke volume rise. The sensitivity and specificity for these thresholds were identical at 89% and 100%. These data are similar to previous investigations in healthy volunteers monitored by the wearable ultrasound.
颈总动脉多普勒超声用于推断心排量变化，现已设计出一种可穿戴式多普勒超声以改善该工作流程。先前，在一项包含约 50000 个心动周期的出血和复苏人体模型中，我们发现心排量变化与颈动脉多普勒信号的测量值之间存在很强的线性相关性，然而，尚未报道用于检测 10%心排量变化的最佳多普勒阈值。在本研究报告中，我们提出了这些阈值及其敏感性、特异性和接收器操作特性曲线下面积（AUROC）。
颈总动脉最大速度时间积分和校正血流时间分别增加 18%和 4%，可准确捕捉到 10%的心排量升高。这些阈值的敏感性和特异性均为 89%和 100%。这些数据与之前使用可穿戴式超声监测的健康志愿者的研究结果相似。
