Department of Anthropology, Panjab University, Chandigarh, India.
Menopause. 2022 Jan 10;29(2):170-177. doi: 10.1097/GME.0000000000001910.
Menopause is a natural phenomenon among women during their midlife, which is accompanied by unfavorable physical, physiological, and psychological consequences. Therefore, the major aim of the present cross-sectional study was to examine whether the cognitive performance of women is sensitive to the severity of menopausal symptoms.
A total number of 404 rural women aged between 40 and 65 years were included in the present study. The menopausal symptoms and cognitive performance of the women were assessed using the Greene Climacteric Scale and Hindi Mini-Mental State Examination scale respectively.
The results of the present study demonstrated that women experiencing severe menopausal symptoms (higher Total Greene climacteric score) presented significantly lower mean values for orientation (8.11 vs 8.90, P < 0.001), registration (2.77 vs 2.91, P < 0.001), attention (4.31 vs 4.48, P < 0.01), recall (2.26 vs 2.53, P < 0.05), and language/visuo-spatial skills (7.13 vs 7.91, P < 0.001) as compared with their counterparts with mild menopausal symptoms. The multivariate linear regression model (after adjustment for age, marital status, and educational status) recorded severe depression and greater sexual dysfunction as the factors significantly associated with lower Mini-Mental State Examination scores.
Hence, the findings of the present study indicated that the cognitive performance of women was sensitive to severe depression and sexual dysfunction.
绝经是女性中年时期的一种自然现象，伴随着身体、生理和心理方面的不利后果。因此，本横断面研究的主要目的是研究女性的认知表现是否对绝经症状的严重程度敏感。
本研究共纳入 404 名年龄在 40 至 65 岁之间的农村妇女。使用 Greene 绝经量表和印地语简易精神状态检查量表分别评估女性的绝经症状和认知表现。
本研究结果表明，经历严重绝经症状（较高的总 Greene 绝经评分）的女性在定向（8.11 与 8.90，P<0.001）、登记（2.77 与 2.91，P<0.001）、注意力（4.31 与 4.48，P<0.01）、回忆（2.26 与 2.53，P<0.05）和语言/视空间技能（7.13 与 7.91，P<0.001）方面的平均得分明显较低。多变量线性回归模型（调整年龄、婚姻状况和教育程度后）记录了严重抑郁和更大的性功能障碍是与简易精神状态检查得分较低显著相关的因素。
因此，本研究的结果表明，女性的认知表现对严重抑郁和性功能障碍敏感。
