Department of Obstetrics and Gynecology, Hadassah Hebrew University Medical Center, Jerusalem, Israel.
Eur J Obstet Gynecol Reprod Biol. 2013 Sep;170(1):229-34. doi: 10.1016/j.ejogrb.2013.06.018. Epub 2013 Jul 15.
To assess the association between demographic and lifestyle parameters and perceived severity of the climacteric syndrome in perimenopausal women.
A cross-sectional study of 151 healthy women aged 45-55 years who attended the University Medical Center affiliated menopause clinics. The analysis was based on self completion of the Greene climacteric score, consisting of psychological, somatic/physical, sexual and vasomotor subscores. The Greene total score and subscores were the main outcomes of the study.
Of all demographic, anthropometric and lifestyle parameters recorded, the correlates with reduced total Greene score were high-order maternity and regular physical exercise. Mothers of 3 or more children reported significantly lower total Greene score (18±12.8 vs. 22.1±8.1) (p=0.01) as well as lower psychological subscore (8.7±6.8 vs. 11.5±5.4) (p=0.01). Regular physical activity was also associated with significantly lower total Greene score (17.0±11.0 vs. 22.6±11.3) (p=0.01) and specifically lower psychological subscore (9.5±6.6 vs. 12.8±7.7) (p=0.03) and sexual subscore (1.1±0.99 vs. 1.61±1.05) (p=0.03). Linear regression models showed that regular exercise was the lifestyle parameter most significantly correlated with a lower total Greene score (p=0.006) independent of menopausal status. Of particular note, regular exercise was significantly correlated with lower psychological (p=0.006) and physical subscores (p=0.06). Moreover, the higher the frequency of exercise (both aerobic and non aerobic), the lower the severity of the climacteric symptoms reported, yet the vasomotor and sexual subscores remained unchanged.
Regular exercise of at least 3 times a week was the most significant lifestyle parameter to be associated with the severity of climacteric symptoms.
评估人口统计学和生活方式参数与围绝经期妇女更年期综合征严重程度感知之间的关系。
这是一项横断面研究，共纳入了 151 名年龄在 45-55 岁之间、在大学医学中心附属更年期诊所就诊的健康女性。分析基于自行填写的格林绝经评分（包括心理、躯体/物理、性和血管舒缩亚评分）。格林总评分和亚评分是本研究的主要结果。
在所记录的所有人口统计学、人体测量学和生活方式参数中，与总格林评分降低相关的因素是多胎生育和定期体育锻炼。生育 3 个或以上孩子的母亲报告的总格林评分明显更低（18±12.8 对 22.1±8.1）（p=0.01），以及心理亚评分更低（8.7±6.8 对 11.5±5.4）（p=0.01）。定期体育锻炼也与总格林评分明显降低相关（17.0±11.0 对 22.6±11.3）（p=0.01），特别是心理亚评分（9.5±6.6 对 12.8±7.7）（p=0.03）和性亚评分（1.1±0.99 对 1.61±1.05）（p=0.03）降低相关。线性回归模型显示，定期锻炼是与总格林评分降低相关性最显著的生活方式参数（p=0.006），与绝经状态无关。值得注意的是，定期锻炼与心理亚评分显著相关（p=0.006）和躯体/物理亚评分显著相关（p=0.06）。此外，锻炼的频率越高（有氧运动和非有氧运动），报告的更年期症状严重程度越低，但血管舒缩和性亚评分保持不变。
至少每周进行 3 次的有规律的运动是与更年期症状严重程度最相关的生活方式参数。
