Department of Zoology, University of Oxford, Oxford, United Kingdom.
Biosystems and Integrative Sciences Institute, Edificio TecLabs, Campus da FCUL, Lisboa, Portugal.
Commun Biol. 2022 Jan 10;5(1):6. doi: 10.1038/s42003-021-02969-3.
It is unclear whether West Nile virus (WNV) circulates endemically in Portugal. Despite the country's adequate climate for transmission, Portugal has only reported four human WNV infections so far. We performed a review of WNV-related data (1966-2020), explored mosquito (2016-2019) and land type distributions (1992-2019), and used climate data (1981-2019) to estimate WNV transmission suitability in Portugal. Serological and molecular evidence of WNV circulation from animals and vectors was largely restricted to the south. Land type and climate-driven transmission suitability distributions, but not the distribution of WNV-capable vectors, were compatible with the North-South divide present in serological and molecular evidence of WNV circulation. Our study offers a comprehensive, data-informed perspective and review on the past epidemiology, surveillance and climate-driven transmission suitability of WNV in Portugal, highlighting the south as a subregion of importance. Given the recent WNV outbreaks across Europe, our results support a timely change towards local, active surveillance.
目前尚不清楚西尼罗河病毒（WNV）在葡萄牙是否存在地方性流行。尽管葡萄牙的气候条件非常有利于传播，但迄今为止，该国仅报告了 4 例人类 WNV 感染病例。我们对与 WNV 相关的数据（1966-2020 年）进行了回顾，探索了蚊子（2016-2019 年）和土地类型分布（1992-2019 年），并使用气候数据（1981-2019 年）来估计 WNV 在葡萄牙的传播适宜性。动物和媒介中WNV 循环的血清学和分子证据主要局限于南部。土地类型和气候驱动的传播适宜性分布，但不是有能力传播 WNV 的蚊子的分布，与WNV 循环的血清学和分子证据中存在的南北分歧相吻合。我们的研究提供了对葡萄牙过去 WNV 流行病学、监测和气候驱动传播适宜性的全面、数据驱动的视角和回顾，强调南部是一个重要的次区域。鉴于欧洲最近发生的 WNV 疫情，我们的研究结果支持及时转向本地、主动监测。
