Postgraduate Program in Food Sciences, Faculty of Pharmacy, 28111Federal University of Bahia, Salvador, Bahia, Brazil.
School of Nutrition, Department of Nutrition Sciences, Federal University of Bahia, Salvador, Bahia, Brazil.
Nutr Health. 2022 Sep;28(3):401-415. doi: 10.1177/02601060211073236. Epub 2022 Jan 11.
Green tea, obtained from the plant , is one of the oldest drinks in the world and contains numerous bioactive compounds. Studies have demonstrated the efficacy of green tea in preventing obesity and cardiovascular diseases that may be related to the reduction of lipid levels. This study aimed to evidence, through a systematic review, the therapeutic potential of green tea on the lipid profile in preclinical studies in obese animals and clinical studies in obese individuals. This systematic review follows the recommendations of the preferred report items for systematic reviews and meta-analyses. The electronic databases, PubMed (Medline), Science Direct, Scopus, and Web of Science were consulted. Articles from January 2009 to December 2019 were selected. This search resulted in twenty-nine articles were included cirtically reviewed. In experimental studies, green tea administration has been shown to reduce total cholesterol, triglycerides and low-density lipoprotein cholesterol in animals exposed to obesity-inducing diet. In humans' studies green tea was not shown to be effective for obese lipid control. Because supplementation with green tea extract reduced total cholesterol, triglycerides, low-density lipoprotein for three months at a specific dose. Therefore, green tea appears to act as a protective agent for dyslipidemia in obesity-induced animals. In human studies, green tea has not been shown to be effective in controlling obese lipids.
绿茶是从植物中提取的，是世界上最古老的饮料之一，含有许多生物活性化合物。研究表明，绿茶在预防肥胖和心血管疾病方面具有功效，这可能与降低血脂水平有关。本研究旨在通过系统评价，证明绿茶对肥胖动物的临床前研究和肥胖个体的临床研究中的血脂谱的治疗潜力。本系统评价遵循系统评价和荟萃分析的首选报告项目的建议。检索了电子数据库 PubMed（Medline）、Science Direct、Scopus 和 Web of Science。选择了 2009 年 1 月至 2019 年 12 月的文章进行批判性回顾。本次检索共纳入 29 篇文章。在实验研究中，绿茶的给药已被证明可降低暴露于致肥胖饮食的动物中的总胆固醇、甘油三酯和低密度脂蛋白胆固醇。在人类研究中，绿茶对肥胖人群的脂质控制没有显示出效果。因为绿茶提取物在特定剂量下补充三个月可降低总胆固醇、甘油三酯和低密度脂蛋白。因此，绿茶似乎对肥胖诱导的动物的血脂异常起到保护作用。在人类研究中，绿茶对控制肥胖人群的血脂没有显示出效果。
