• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Designing nanocarriers to overcome the limitations in conventional drug administration for Parkinson's disease.

作者信息

Garcia-Munoz Rafael A, McConnell Joseph, Morales Victoria, Sanz Raul

机构信息

Department of Chemical and Environmental Technology, Rey Juan Carlos University, Madrid, Spain.

Department of Chemical & Process Engineering, University of Strathclyde, Glasgow, UK.

出版信息

Neural Regen Res. 2022 Aug;17(8):1743-1744. doi: 10.4103/1673-5374.332143.

DOI:10.4103/1673-5374.332143
PMID:35017428
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8820718/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f0b/8820718/be2fe655a5a9/NRR-17-1743-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f0b/8820718/be2fe655a5a9/NRR-17-1743-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f0b/8820718/be2fe655a5a9/NRR-17-1743-g001.jpg

相似文献

1
Designing nanocarriers to overcome the limitations in conventional drug administration for Parkinson's disease.设计纳米载体以克服帕金森病传统药物给药方式的局限性。
Neural Regen Res. 2022 Aug;17(8):1743-1744. doi: 10.4103/1673-5374.332143.
2
In vivo biodistribution of prion- and GM1-targeted polymersomes following intravenous administration in mice.静脉注射后,朊病毒和 GM1 靶向聚合物囊泡在小鼠体内的生物分布。
Mol Pharm. 2012 Jun 4;9(6):1620-7. doi: 10.1021/mp200621v. Epub 2012 May 7.
3
Intranasal delivery of mucoadhesive nanocarriers: a viable option for Parkinson's disease treatment?鼻腔内递送达玛烷型二萜类化合物纳米载体:帕金森病治疗的可行选择?
Expert Opin Drug Deliv. 2019 Dec;16(12):1355-1366. doi: 10.1080/17425247.2019.1684895. Epub 2019 Nov 8.
4
Nanocarriers as a powerful vehicle to overcome blood-brain barrier in treating neurodegenerative diseases: Focus on recent advances.纳米载体作为治疗神经退行性疾病中克服血脑屏障的有力工具:聚焦于近期进展
Asian J Pharm Sci. 2019 Sep;14(5):480-496. doi: 10.1016/j.ajps.2018.09.005. Epub 2018 Oct 22.
5
Micellar Nanocarriers of Hydroxytyrosol Are Protective against Parkinson's Related Oxidative Stress in an In Vitro hCMEC/D3-SH-SY5Y Co-Culture System.羟基酪醇的胶束纳米载体在体外人脑血管内皮细胞hCMEC/D3-神经母细胞瘤细胞SH-SY5Y共培养系统中对帕金森病相关氧化应激具有保护作用。
Antioxidants (Basel). 2021 May 31;10(6):887. doi: 10.3390/antiox10060887.
6
N-Acetylcysteine Nanocarriers Protect against Oxidative Stress in a Cellular Model of Parkinson's Disease.N-乙酰半胱氨酸纳米载体在帕金森病细胞模型中对抗氧化应激
Antioxidants (Basel). 2020 Jul 9;9(7):600. doi: 10.3390/antiox9070600.
7
Monitoring Parkinson's disease symptoms during daily life: a feasibility study.日常生活中帕金森病症状的监测:一项可行性研究。
NPJ Parkinsons Dis. 2019 Sep 30;5:21. doi: 10.1038/s41531-019-0093-5. eCollection 2019.
8
Nanocarriers as Administration Systems of Natural Products.纳米载体作为天然产物的给药系统。
Curr Top Med Chem. 2021;21(26):2365-2373. doi: 10.2174/1568026621666210915121957.
9
Designing peptide nanoparticles for efficient brain delivery.设计用于高效脑递送的肽纳米粒。
Adv Drug Deliv Rev. 2020;160:52-77. doi: 10.1016/j.addr.2020.10.001. Epub 2020 Oct 5.
10
Nanocarriers for the Effective Treatment of Cervical Cancer: Research Advancements and Patent Analysis.用于有效治疗宫颈癌的纳米载体:研究进展与专利分析
Recent Pat Drug Deliv Formul. 2018;12(2):93-109. doi: 10.2174/1872211312666180403102019.

引用本文的文献

1
Nanoparticle Strategies for Treating CNS Disorders: A Comprehensive Review of Drug Delivery and Theranostic Applications.治疗中枢神经系统疾病的纳米颗粒策略:药物递送与诊疗应用综述
Int J Mol Sci. 2024 Dec 11;25(24):13302. doi: 10.3390/ijms252413302.
2
Architecture-Aware Augmentation: A Hybrid Deep Learning and Machine Learning Approach for Enhanced Parkinson's Disease Detection.架构感知增强:一种用于增强帕金森病检测的深度学习与机器学习混合方法。
Bioengineering (Basel). 2024 Dec 2;11(12):1218. doi: 10.3390/bioengineering11121218.

本文引用的文献

1
Neurotrophic Factors in Parkinson's Disease: Clinical Trials, Open Challenges and Nanoparticle-Mediated Delivery to the Brain.帕金森病中的神经营养因子:临床试验、公开挑战及纳米颗粒介导的脑内递送
Front Cell Neurosci. 2021 Jun 2;15:682597. doi: 10.3389/fncel.2021.682597. eCollection 2021.
2
L-Dopa release from mesoporous silica nanoparticles engineered through the concept of drug-structure-directing agents for Parkinson's disease.通过药物结构导向剂的概念设计用于治疗帕金森病的介孔硅纳米粒子中左旋多巴的释放。
J Mater Chem B. 2021 May 26;9(20):4178-4189. doi: 10.1039/d1tb00481f.
3
Bioinspired Theranostic Coordination Polymer Nanoparticles for Intranasal Dopamine Replacement in Parkinson's Disease.
仿生治疗协同聚合物纳米粒子用于帕金森病的鼻腔内多巴胺替代治疗。
ACS Nano. 2021 May 25;15(5):8592-8609. doi: 10.1021/acsnano.1c00453. Epub 2021 Apr 22.
4
Challenges and Opportunities of Deferoxamine Delivery for Treatment of Alzheimer's Disease, Parkinson's Disease, and Intracerebral Hemorrhage.去铁胺递药用于治疗阿尔茨海默病、帕金森病和脑出血的挑战与机遇。
Mol Pharm. 2021 Feb 1;18(2):593-609. doi: 10.1021/acs.molpharmaceut.0c00474. Epub 2020 Oct 9.
5
Continuous Drug Delivery Aiming Continuous Dopaminergic Stimulation in Parkinson's Disease.持续药物输送以实现帕金森病的持续多巴胺刺激。
J Parkinsons Dis. 2018;8(s1):S65-S72. doi: 10.3233/JPD-181476.
6
Micro- and nanotechnology approaches to improve Parkinson's disease therapy.微纳技术在改善帕金森病治疗中的应用
J Control Release. 2019 Feb 10;295:201-213. doi: 10.1016/j.jconrel.2018.12.036. Epub 2018 Dec 21.
7
Overcoming the Blood-Brain Barrier: The Role of Nanomaterials in Treating Neurological Diseases.克服血脑屏障:纳米材料在治疗神经疾病中的作用。
Adv Mater. 2018 Nov;30(46):e1801362. doi: 10.1002/adma.201801362. Epub 2018 Jul 31.
8
Trans-blood brain barrier delivery of dopamine-loaded nanoparticles reverses functional deficits in parkinsonian rats.载多巴胺纳米粒经血脑屏障递送至帕金森病大鼠模型中可逆转其功能缺陷。
ACS Nano. 2015 May 26;9(5):4850-71. doi: 10.1021/nn506408v. Epub 2015 Apr 22.
9
Nanoparticles in relation to peptide and protein aggregation.与肽和蛋白质聚集相关的纳米颗粒
Int J Nanomedicine. 2014 Feb 12;9:899-912. doi: 10.2147/IJN.S54171. eCollection 2014.