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Int J Nanomedicine. 2020 May 6;15:3207-3215. doi: 10.2147/IJN.S243202. eCollection 2020.
3
Silver nanoparticles in dentistry.牙科中的银纳米颗粒。
Dent Mater. 2017 Oct;33(10):1110-1126. doi: 10.1016/j.dental.2017.07.002. Epub 2017 Aug 2.
4
UCSF Protocol for Caries Arrest Using Silver Diamine Fluoride: Rationale, Indications and Consent.加州大学旧金山分校使用氟化亚锡铵进行龋齿抑制的方案：基本原理、适应症及同意书
J Calif Dent Assoc. 2016 Jan;44(1):16-28.
5
X-ray absorption near-edge structure (XANES) spectroscopy study of the interaction of silver ions with Staphylococcus aureus, Listeria monocytogenes, and Escherichia coli.X 射线吸收近边结构（XANES）光谱研究银离子与金黄色葡萄球菌、单核细胞增生李斯特菌和大肠杆菌的相互作用。
Appl Environ Microbiol. 2013 Oct;79(20):6385-90. doi: 10.1128/AEM.01688-13. Epub 2013 Aug 9.
6
Perspectives for the use of silver nanoparticles in dental practice.银纳米粒子在牙科实践中的应用展望。
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Silver diamine fluoride: a caries "silver-fluoride bullet".氟化亚银：一颗治疗龋齿的“氟化银子弹”。
J Dent Res. 2009 Feb;88(2):116-25. doi: 10.1177/0022034508329406.
8
Biological synthesis of silver and gold nanoparticles using apiin as reducing agent.以芹菜苷为还原剂生物合成银和金纳米颗粒。
Colloids Surf B Biointerfaces. 2009 Jan 1;68(1):55-60. doi: 10.1016/j.colsurfb.2008.09.021. Epub 2008 Sep 30.
9
From vulcanite to vinyl, a history of resins in restorative dentistry.从硬质橡胶到乙烯基：口腔修复学中树脂的历史
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10
In vitro antibacterial activity of a glass ionomer endodontic sealer.玻璃离子根管封闭剂的体外抗菌活性
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银纳米颗粒绿色合成对致龋病原体的抗菌效果——一项研究

Antimicrobial Efficacy of Green Synthesis of Silver Nanoparticles against Cariogenic Pathogens - An Study.

作者信息

Chittrarasu M, Ahamed A Shafie, Ravi Vaiyapuri

机构信息

Department of Conservative, Dentistry and Endodontics, Vivekanandha Dental College for Women, Namakkal, The Tamil Nadu Dr. M.G.R. Medical University, Tamil Nadu, India.

Department of Conservative Dentistry and Endodontics, Rajah Muthiah Dental College, Annamalai University, Annamalai Nagar, Tamil Nadu, India.

出版信息

J Pharm Bioallied Sci. 2021 Nov;13(Suppl 2):S1188-S1192. doi: 10.4103/jpbs.jpbs_338_21. Epub 2021 Nov 10.

DOI:10.4103/jpbs.jpbs_338_21
PMID:35017954
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8686925/
Abstract

BACKGROUND

Nowadays, emergence of drug resistance might happen in the world. Hence, invention of new dental material had started by researchers for the same. The present study evaluated the antimicrobial property of green synthesized nanosilver particles against dental cariogenic microorganisms such as and .

MATERIALS AND METHODS

An study had been designed to meet the objectives. Galla Chinensis ellagic acid powder synthesized nanosilver particles (GCAgNPs) synthesized nanosilver particles were used in this study. The cariogenic bacteria (ATCC 25175) and (ATCC 4356) were used in this study. The antimicrobial activity was detected at different concentrations (1000 μg/ml, 500 μg/ml, 250 μg/ml, 125 μg/ml, and 62.5 μg/ml) by means of qualitative and quantitative methods.

RESULTS

The results show a statistically significant difference between all the concentration (1000 μg/ml, 500 μg/ml, 250 μg/ml, 125 μg/ml, 62.5 μg/ml) in Galla Chinensis synthesized silver nanoparticles (GCAgNPs) in and . Intergroup comparison of GCAgNPs shows a statistically significant difference among all the concentrations against and .

CONCLUSION

GCAgNPs show antimicrobial and antibiofilm activity against and microorganisms.

摘要

背景

如今，耐药性在全球范围内可能出现。因此，研究人员已开始研发新型牙科材料。本研究评估了绿色合成纳米银颗粒对变形链球菌和远缘链球菌等致龋微生物的抗菌性能。

材料与方法

设计了一项研究以实现这些目标。本研究使用了五倍子鞣花酸粉末合成的纳米银颗粒（GCAgNPs）。本研究中使用了致龋细菌变形链球菌（ATCC 25175）和远缘链球菌（ATCC 4356）。通过定性和定量方法检测了不同浓度（1000μg/ml、500μg/ml、250μg/ml、125μg/ml和62.5μg/ml）下的抗菌活性。

结果

结果表明，五倍子合成的银纳米颗粒（GCAgNPs）在1000μg/ml、500μg/ml、250μg/ml、125μg/ml、62.5μg/ml所有浓度下，在变形链球菌和远缘链球菌中的差异具有统计学意义。GCAgNPs的组间比较显示，在所有浓度下对变形链球菌和远缘链球菌的差异具有统计学意义。

结论

GCAgNPs对变形链球菌和远缘链球菌微生物显示出抗菌和抗生物膜活性。