Jana Sonali, Das Piyali, Mukherjee Joydip, Banerjee Dipak, Ghosh Prabal Ranjan, Kumar Das Pradip, Bhattacharya Rup Narayan, Nandi Samit Kumar
Department of Veterinary Physiology, West Bengal University of Animal and Fishery Sciences, Kolkata 700037, India.
Department of Microbiology, School of Life Sciences and Biotechnology, Adamas University, Barasat, West Bengal 700126, India.
J Mater Chem B. 2022 Jan 26;10(4):489-505. doi: 10.1039/d1tb02125g.
Recent developments in the biomedical arena have led to the fabrication of innovative biomaterials by utilizing bioactive molecules obtained from biological wastes released from fruit and beverage processing industries, and fish, meat, and poultry industries. These biological wastes that end up in water bodies as well as in landfills are an affluent source of animal- and plant-derived proteins, bio ceramics and polysaccharides such as collagens, gelatins, chitins, chitosans, eggshell membrane proteins, hydroxyapatites, celluloses, and pectins. These bioactive molecules have been intricately designed into scaffolds and dressing materials by utilizing advanced technologies for drug delivery, tissue engineering, and wound healing relevance. These biomaterials are environment-friendly, biodegradable, and biocompatible, and show excellent tissue regeneration attributes. Additionally, being cost-effective they can reduce the burden on the healthcare system as well as provide a sustainable solution to waste management. In this review, the current trends in the utilization of plant and animal waste-derived biomaterials in various biomedical fields are considered along with a separate section on their applications as xenografts.
生物医学领域的最新进展促使人们利用从水果和饮料加工业以及鱼类、肉类和家禽业产生的生物废物中提取的生物活性分子来制造创新型生物材料。这些最终进入水体和垃圾填埋场的生物废物是动植物源蛋白质、生物陶瓷和多糖（如胶原蛋白、明胶、几丁质、壳聚糖、蛋壳膜蛋白、羟基磷灰石、纤维素和果胶）的丰富来源。通过利用先进的药物递送、组织工程和伤口愈合相关技术，这些生物活性分子被精心设计成支架和敷料材料。这些生物材料环保、可生物降解且具有生物相容性，并展现出优异的组织再生特性。此外，由于具有成本效益，它们可以减轻医疗保健系统的负担，并为废物管理提供可持续的解决方案。在本综述中，我们考虑了在各种生物医学领域中利用植物和动物废物衍生生物材料的当前趋势，并单独设立一节介绍它们作为异种移植物的应用。
